AC   MF_01286;
DC   Protein; auto
TR   HAMAP; MF_01286; -; 1; level=0
XX
Names: DGGGP_synth
XX
ID   DGGGP
DE   RecName: Full=Digeranylgeranylglyceryl phosphate synthase;
DE            Short=DGGGP synthase;
DE            Short=DGGGPS;
DE            EC=2.5.1.42;
DE   AltName: Full=(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase;
DE   AltName: Full=Geranylgeranylglycerol-phosphate geranylgeranyltransferase;
XX
CC   -!- FUNCTION: Prenyltransferase that catalyzes the transfer of the
CC       geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2
CC       hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This
CC       reaction is the second ether-bond-formation step in the biosynthesis of
CC       archaeal membrane lipids.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2E,6E,10E)-geranylgeranyl diphosphate + sn-3-O-
CC         (geranylgeranyl)glycerol 1-phosphate = 2,3-bis-O-(geranylgeranyl)-sn-
CC         glycerol 1-phosphate + diphosphate; Xref=Rhea:RHEA:18109,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:57677, ChEBI:CHEBI:58756,
CC         ChEBI:CHEBI:58837; EC=2.5.1.42;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC   -!- PATHWAY: Membrane lipid metabolism; glycerophospholipid metabolism.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the UbiA prenyltransferase family. DGGGP
CC       synthase subfamily.
XX
DR   Pfam; PF01040; UbiA; 1; trigger=no
DR   General; Transmembrane; -; 5-9; trigger=yes
XX
KW   Cell membrane
KW   Lipid biosynthesis
KW   Lipid metabolism
KW   Magnesium
KW   Membrane
KW   Phospholipid biosynthesis
KW   Phospholipid metabolism
KW   Transferase
KW   Transmembrane
KW   Transmembrane helix
XX
GO   GO:0000287; F:magnesium ion binding
GO   GO:0047295; F:geranylgeranylglycerol-phosphate geranylgeranyltransferase activity
GO   GO:0008654; P:phospholipid biosynthetic process
GO   GO:0005886; C:plasma membrane
XX
FT   None
XX
Size: 267-303;
Related: None;
Template: Q9UWY6; O27170;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.12 2021/03/29
//