AC   MF_01321;
DC   Protein; auto
TR   HAMAP; MF_01321; -; 1; level=0
XX
Names: RNApol_bact_RpoB
XX
ID   RPOB
case not <OG:Chloroplast>
DE   RecName: Full=DNA-directed RNA polymerase subunit beta;
DE            Short=RNAP subunit beta;
DE            EC=2.7.7.6;
DE   AltName: Full=RNA polymerase subunit beta;
DE   AltName: Full=Transcriptase subunit beta;
else case <OG:Chloroplast>
DE   RecName: Full=DNA-directed RNA polymerase subunit beta;
DE            EC=2.7.7.6;
DE   AltName: Full=PEP;
DE   AltName: Full=Plastid-encoded RNA polymerase subunit beta;
DE            Short=RNA polymerase subunit beta;
end case
GN   Name=rpoB;
XX
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6;
case not <OG:Chloroplast> and not <OC:Cyanobacteriota>
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta'
CC       and 1 omega subunit. When a sigma factor is associated with the core
CC       the holoenzyme is formed, which can initiate transcription.
else case <OC:Cyanobacteriota>
CC   -!- SUBUNIT: In cyanobacteria the RNAP catalytic core is composed of 2
CC       alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma
CC       factor is associated with the core the holoenzyme is formed, which can
CC       initiate transcription.
else case <OG:Chloroplast>
CC   -!- SUBUNIT: In plastids the minimal PEP RNA polymerase catalytic core is
CC       composed of four subunits: alpha, beta, beta', and beta''. When a
CC       (nuclear-encoded) sigma factor is associated with the core the
CC       holoenzyme is formed, which can initiate transcription.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
end case
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
XX
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1; trigger=no
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 1; trigger=no
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1; trigger=no
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1; trigger=no
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1; trigger=no
DR   NCBIfam; TIGR02013; RpoB; 1; trigger=no
DR   PROSITE; PS01166; RNA_POL_BETA; 1; trigger=no
XX
case (<OC:Escherichia> or <OC:Shigella>) and (<FT:1> or <FT:2>)
KW   Acetylation
end case
KW   Transcription
KW   Transferase
KW   Nucleotidyltransferase
KW   DNA-directed RNA polymerase
XX
GO   GO:0003677; F:DNA binding
GO   GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity
GO   GO:0006351; P:DNA-templated transcription
case <OG:Chloroplast>
GO   GO:0009507; C:chloroplast
end case
XX
FT   From: RPOB_ECOLI (P0A8V2)
case <OC:Escherichia> or <OC:Shigella>
FT   MOD_RES         1022
FT                   /note="N6-acetyllysine"
FT   Condition: K
FT   MOD_RES         1200
FT                   /note="N6-acetyllysine"
FT   Condition: K
end case
XX
Size: 1060-1499;
Related: None;
Template: Q9KWU7; P0A8V2;
Scope:
 Bacteria
 Plastid
Fusion:
 Nter: None
 Cter: MF_01322 (rpoC)
Duplicate: in CLOBH, NOCFA, CERS1
Plasmid: in SHEB5
Comments: Fused with rpoC in Helicobacter species and at least some
 Wolbachia, but not in other epsilon proteobateria.
 CHLVU, ODOSI and PSEAK have large inserts, HETCA has a deletion, CHLRE is split.
 None are used in the alignment.
XX
# Revision 1.35 2023/06/01
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