AC   MF_01323;
DC   Protein; auto
TR   HAMAP; MF_01323; -; 1; level=0
XX
Names: RNApol_bact_RpoC1
XX
ID   RPOC1
case not <OG:Chloroplast>
DE   RecName: Full=DNA-directed RNA polymerase subunit gamma;
DE            Short=RNAP subunit gamma;
DE            EC=2.7.7.6;
DE   AltName: Full=RNA polymerase subunit gamma;
DE   AltName: Full=Transcriptase subunit gamma;
else case <OG:Chloroplast>
DE   RecName: Full=DNA-directed RNA polymerase subunit beta';
DE            EC=2.7.7.6;
DE   AltName: Full=PEP;
DE   AltName: Full=Plastid-encoded RNA polymerase subunit beta';
DE            Short=RNA polymerase subunit beta';
end case
GN   Name=rpoC1;
XX
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC       DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.6;
case <FTGroup:2>
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC       Note=Binds 1 Mg(2+) ion per subunit.;
end case
case <FTGroup:1>
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 1 Zn(2+) ion per subunit.;
end case
case <OC:Cyanobacteriota>
CC   -!- SUBUNIT: In cyanobacteria the RNAP catalytic core is composed of 2
CC       alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma
CC       factor is associated with the core the holoenzyme is formed, which can
CC       initiate transcription.
else case <OG:Chloroplast>
CC   -!- SUBUNIT: In plastids the minimal PEP RNA polymerase catalytic core is
CC       composed of four subunits: alpha, beta, beta', and beta''. When a
CC       (nuclear-encoded) sigma factor is associated with the core the
CC       holoenzyme is formed, which can initiate transcription.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
end case
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family. RpoC1
CC       subfamily.
XX
DR   Pfam; PF04997; RNA_pol_Rpb1_1; 1; trigger=no
DR   Pfam; PF00623; RNA_pol_Rpb1_2; 1-2; trigger=no
DR   Pfam; PF04983; RNA_pol_Rpb1_3; 0-1; trigger=no
DR   NCBIfam; TIGR02387; rpoC1_cyan; 1; trigger=no
XX
case <FTGroup:1> or <FTGroup:2>
KW   Metal-binding
end case
case <FTGroup:2>
KW   Magnesium
end case
KW   Transcription
KW   Transferase
KW   Nucleotidyltransferase
KW   DNA-directed RNA polymerase
case <FTGroup:1>
KW   Zinc
end case
XX
GO   GO:0003677; F:DNA binding
GO   GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity
GO   GO:0006351; P:DNA-templated transcription
case <FTGroup:2>
GO   GO:0000287; F:magnesium ion binding
end case
case <FTGroup:1>
GO   GO:0008270; F:zinc ion binding
end case
case <OG:Chloroplast>
GO   GO:0009507; C:chloroplast
end case
XX
FT   From: RPOC1_NOSS1 (P22704)
FT   BINDING         71
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         73
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         86
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         89
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         467
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Group: 2; Condition: D
FT   BINDING         469
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Group: 2; Condition: D
FT   BINDING         471
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Group: 2; Condition: D
XX
Size: 575-760;
Related: MF_01322!;
Template: P22704; P11705;
Scope:
 Bacteria; Cyanobacteriota
 Plastid
Fusion:
 Nter: None
 Cter: MF_01324 (rpoC2)
Duplicate: None
Plasmid: None
Comments: In cyanobacteria and plastids, there are two ORFs (this one, rpoC1,
 MF_01323 and rpoC2, MF_01324) that together are equivalent to the beta'
 subunit found in all other bacteria (rpoC, MF_01322).
 However,in the red algae CYAM1 the rpoC1 and rpoC2 genes are fused into
 one ORF. This seems to be the result of evolution acting to reduce protein
 size rather than horizontal transfer from a bacteria.
 Some algal proteins with inserts and C.reinhardtii (where this protein is
 split in 2) are considered to be atypical.
XX
# Revision 1.36 2023/06/01
//