AC   MF_01367;
DC   Protein; auto
c?   <OC:Bacteria> or <OC:Archaea> or <OG:Chloroplast>
TR   HAMAP; MF_01367; -; 1; level=0
XX
Names: Ribosomal_uL14
XX
case <OC:Bacteria> and not <OC:Cyanobacteriota>
ID   RL14
DE   RecName: Full=Large ribosomal subunit protein uL14;
GN   Name=rplN;
else case <OC:Cyanobacteriota>
ID   RL14
DE   RecName: Full=Large ribosomal subunit protein uL14;
GN   Name=rplN; Synonyms=rpl14;
else case <OC:Archaea>
ID   RL14
DE   RecName: Full=Large ribosomal subunit protein uL14;
GN   Name=rpl14;
else case <OG:Chloroplast>
ID   RK14
DE   RecName: Full=Large ribosomal subunit protein uL14c;
GN   Name=rpl14;
end case
XX
case <OC:Bacteria>
CC   -!- FUNCTION: Binds to 23S rRNA. Forms part of two intersubunit bridges in
CC       the 70S ribosome.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC       proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and
CC       together make contacts with the 16S rRNA in bridges B5 and B8.
else case <OC:Archaea>
CC   -!- FUNCTION: Binds to 23S rRNA. Forms part of two intersubunit bridges in
CC       the 70S ribosome.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC       proteins L3 and L24e, part of which may contact the 16S rRNA in 2
CC       intersubunit bridges.
else case <OG:Chloroplast>
CC   -!- FUNCTION: Binds to 23S rRNA.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
end case
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL14 family.
XX
DR   PROSITE; PS00049; RIBOSOMAL_L14; 1; trigger=no
DR   Pfam; PF00238; Ribosomal_L14; 1; trigger=no
DR   NCBIfam; TIGR01067; RplN_bact; 1; trigger=no
DR   NCBIfam; TIGR03673; rpl14p_arch; 1; trigger=no
XX
KW   Ribonucleoprotein
KW   Ribosomal protein
KW   RNA-binding
KW   rRNA-binding
XX
GO   GO:0019843; F:rRNA binding
GO   GO:0006412; P:translation
case <OG:Chloroplast>
GO   GO:0009507; C:chloroplast
end case
XX
Size: 119-182;
Related: None;
Template: Q9RXJ2; P0ADY3; Q5SHP8; P22450;
Scope:
 Bacteria
 Archaea
 Plastid
Fusion:
 Nter: None
 Cter: None
Duplicate: in BARBK, LEPBL
Plasmid: None
Comments: In E.coli interaction of L14 with ribosomal silencing factor
 RsfS has been shown block formation of bridge B8, preventing association
 of 2 ribosomal subunits and thus causes ribosomal silencing. The same
 interaction is suspected to have the same effect in human mitochondrial
 ribosomes and maybe maize chloroplasts as well. It has not yet been
 propagated to all ribosomal proteins while waiting further experimental
 confirmation.
XX
# Revision 1.22 2023/09/22
//