AC   MF_01377;
DC   Protein; auto
TR   HAMAP; MF_01377; -; 1; level=0
XX
Names: YegS
XX
ID   YEGS
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
DE   RecName: Full=Probable lipid kinase YegS;
DE            EC=2.7.1.-;
GN   Name=yegS;
else
DE   RecName: Full=Probable lipid kinase YegS-like;
DE            EC=2.7.1.-;
end case
XX
CC   -!- FUNCTION: Probably phosphorylates lipids; the in vivo substrate is
CC       unknown.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC       Note=Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the diacylglycerol/lipid kinase family. YegS
CC       lipid kinase subfamily.
XX
DR   Pfam; PF00781; DAGK_cat; 1; trigger=no
DR   NCBIfam; TIGR03702; lip_kinase_YegS; 1; trigger=no
DR   NCBIfam; TIGR00147; TIGR00147; 1; trigger=no
DR   PROSITE; PS50146; DAGK; 1; trigger=yes
XX
KW   ATP-binding
KW   Cytoplasm
KW   Kinase
KW   Lipid biosynthesis
KW   Lipid metabolism
KW   Magnesium
KW   Metal-binding
KW   Nucleotide-binding
KW   Phospholipid biosynthesis
KW   Phospholipid metabolism
KW   Transferase
XX
GO   GO:0000287; F:magnesium ion binding
GO   GO:0001727; F:lipid kinase activity
GO   GO:0005524; F:ATP binding
GO   GO:0008654; P:phospholipid biosynthetic process
GO   GO:0005737; C:cytoplasm
XX
FT   From: YEGS_ECOLI (P76407)
FT   BINDING         66..72
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   ACT_SITE        271
FT                   /note="Proton acceptor"
FT   Condition: E
FT   BINDING         215
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: [LVKRM]
FT   BINDING         218
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: D
FT   BINDING         220
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: L
FT   BINDING         40
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: [TS]
FT   BINDING         95
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: [TS]
XX
Size: 290-340;
Related: None;
Template: P76407; Q8ZNP1;
Scope:
 Bacteria; Gammaproteobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.23 2023/06/01
//