AC   MF_01400;
DC   Protein; auto
TR   HAMAP; MF_01400; -; 1; level=0
XX
Names: MsrB
XX
ID   MSRB
DE   RecName: Full=Peptide methionine sulfoxide reductase MsrB;
DE            EC=1.8.4.12;
DE   AltName: Full=Peptide-methionine (R)-S-oxide reductase;
GN   Name=msrB;
XX
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[thioredoxin]-disulfide + H2O + L-methionyl-[protein] =
CC         [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein];
CC         Xref=Rhea:RHEA:24164, Rhea:RHEA-COMP:10698, Rhea:RHEA-COMP:10700,
CC         Rhea:RHEA-COMP:12313, Rhea:RHEA-COMP:12314, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:16044, ChEBI:CHEBI:29950, ChEBI:CHEBI:45764,
CC         ChEBI:CHEBI:50058; EC=1.8.4.12;
case <FTGroup:1>
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 1 zinc ion per subunit. The zinc ion is important for the
CC       structural integrity of the protein.;
end case
CC   -!- SIMILARITY: Belongs to the MsrB Met sulfoxide reductase family.
XX
DR   Pfam; PF01641; SelR; 1; trigger=no
DR   NCBIfam; TIGR00357; TIGR00357; 1; trigger=no
DR   PROSITE; PS51790; MSRB; 1; trigger=yes
XX
KW   Oxidoreductase
case <FTGroup:1>
KW   Metal-binding
KW   Zinc
end case
XX
GO   GO:0033743; F:peptide-methionine (R)-S-oxide reductase activity
case <FTGroup:1>
GO   GO:0008270; F:zinc ion binding
end case
XX
FT   From: MSRB_ECOLI (P0A746)
FT   ACT_SITE        118
FT                   /note="Nucleophile"
FT   Condition: C
FT   BINDING         46
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Optional; Group: 1; Condition: C
FT   BINDING         49
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Optional; Group: 1; Condition: C
FT   BINDING         95
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Optional; Group: 1; Condition: C
FT   BINDING         98
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Optional; Group: 1; Condition: C
XX
Size: 124-159;
Related: None;
Template: P14930; Q9JWM8; P0A746; Q3JRF0; P0A088;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: MF_01401 (msrA)
 Cter: MF_01401 (msrA)
Duplicate: in RHIME
Plasmid: in RHIME
Comments: None
XX
# Revision 1.33 2023/06/01
//