AC   MF_01415;
DC   Protein; auto
TR   HAMAP; MF_01415; -; 1; level=0
XX
Names: K_H_efflux_KefG
XX
ID   KEFG
DE   RecName: Full=Glutathione-regulated potassium-efflux system ancillary protein KefG;
DE   AltName: Full=Putative quinone oxidoreductase KefG;
DE            EC=1.6.5.2;
GN   Name=kefG;
XX
CC   -!- FUNCTION: Regulatory subunit of a potassium efflux system that confers
CC       protection against electrophiles. Required for full activity of KefB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinone + NADH + H(+) = a quinol + NAD(+);
CC         Xref=Rhea:RHEA:46160, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:132124; EC=1.6.5.2;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinone + NADPH + H(+) = a quinol + NADP(+);
CC         Xref=Rhea:RHEA:46164, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC         ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:132124; EC=1.6.5.2;
CC   -!- SUBUNIT: Interacts with KefB.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein;
CC       Cytoplasmic side.
CC   -!- SIMILARITY: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG
CC       subfamily.
XX
DR   Pfam; PF02525; Flavodoxin_2; 1; trigger=no
XX
KW   Cell inner membrane
KW   Cell membrane
KW   Membrane
KW   NAD
KW   Oxidoreductase
XX
GO   GO:0003955; F:NAD(P)H dehydrogenase (quinone) activity
GO   GO:0032414; P:positive regulation of ion transmembrane transporter activity
GO   GO:1901381; P:positive regulation of potassium ion transmembrane transport
XX
Size: 175-233;
Related: None;
Template: P0A756;
Scope:
 Bacteria; Gammaproteobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: KefF is the ancillary protein of KefC, whereas KefG is the ancillary protein
 of KefB. KefF and KefG cannot complement each other and are specific for their
 respective efflux system.
XX
# Revision 1.17 2024/09/02
//