AC   MF_01484;
DC   Protein; auto
TR   HAMAP; MF_01484; -; 1; level=0
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Names: AcrZ
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ID   ACRZ
DE   RecName: Full=Multidrug efflux pump accessory protein AcrZ;
DE   AltName: Full=AcrAB-TolC multidrug efflux pump accessory protein AcrZ;
DE   AltName: Full=Acridine resistance protein Z;
GN   Name=acrZ;
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CC   -!- FUNCTION: Accessory component of the AcrABZ-TolC efflux protein
CC       complex, which has a broad substrate specificity. Binds to AcrB and
CC       perhaps together with membrane lipids, such as cardiolipin, influences
CC       the specificity of substrate export.
CC   -!- SUBUNIT: Component of the AcrABZ-TolC efflux pump complex.
case not defined <Property:Membrane> or <Property:Membrane=1>
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein.
else case <Property:Membrane=2>
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Single-pass membrane
CC       protein.
end case
CC   -!- SIMILARITY: Belongs to the AcrZ family.
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DR   Pfam; PF10766; DUF2592; 1; trigger=no
DR   General; Transmembrane; -; 1; trigger=yes
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KW   Antibiotic resistance
KW   Cell membrane
case defined <Property:Membrane> and <Property:Membrane=2>
KW   Cell inner membrane
end case
KW   Membrane
KW   Transmembrane
KW   Transmembrane helix
KW   Transport
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GO   GO:0042910; F:xenobiotic transmembrane transporter activity
GO   GO:0005886; C:plasma membrane
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FT   None
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Size: 41-83;
Related: None;
Template: P0AAW9;
Scope:
 Bacteria; Enterobacterales
Fusion:
 Nter: None
 Cter: None
Duplicate: in SERP5, SERSA
Plasmid: None
Comments: The protein is probably about 50 residues long, longer versions
 have a too long N-terminal.
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# Version: 8
# Last updated date: 2025-05-13
# Created date: 2013-10-10
//