AC   MF_01498;
DC   Protein; auto
TR   HAMAP; MF_01498; -; 1; level=0
XX
Names: RadA_bact
XX
ID   RADA
DE   RecName: Full=DNA repair protein RadA;
GN   Name=radA;
XX
CC   -!- FUNCTION: Plays a role in repairing double-strand DNA breaks, probably
CC       involving stabilizing or processing branched DNA or blocked replication
CC       forks.
case <FT:1>
CC   -!- DOMAIN: Has a putative N-terminal zinc-finger, a middle region with
CC       homology to RecA with ATPase motifs including the RadA KNRFG motif,
CC       while the C-terminus is homologous to Lon protease.
else
CC   -!- DOMAIN: The middle region has homology to RecA with ATPase motifs
CC       including the RadA KNRFG motif, while the C-terminus is homologous to
CC       Lon protease.
end case
CC   -!- SIMILARITY: Belongs to the RecA family. RadA subfamily.
XX
DR   PROSITE; PS50162; RECA_2; 1; trigger=no
DR   Pfam; PF05362; Lon_C; 1; trigger=no
DR   PRINTS; PR01874; DNAREPAIRADA; 1; trigger=no
DR   NCBIfam; TIGR00416; sms; 1; trigger=no
XX
KW   ATP-binding
KW   DNA damage
KW   DNA repair
KW   DNA-binding
KW   Metal-binding
KW   Nucleotide-binding
KW   Stress response
case <FT:1>
KW   Zinc
KW   Zinc-finger
end case
XX
GO   GO:0000725; P:recombinational repair
GO   GO:0005524; F:ATP binding
XX
FT   From: RADA_ECOLI (P24554)
FT   ZN_FING         11..28
FT                   /note="C4-type"
FT   Optional; Condition: C-x(2)-C-x(10)-C-x(2)-C
FT   BINDING         102..109
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: [GAS]-x-P-G-x-G-K-[ST]
FT   REGION          357..Cter
FT                   /note="Lon-protease-like"
FT   MOTIF           258..262
FT                   /note="RadA KNRFG motif"
FT   Condition: K-N-R-[FY]-G
XX
Size: 420-505;
Related: None;
Template: P24554; P37572; Q9RVC4; Q8DRP0;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: A number of Streptococcus pneumoniae do not encode the possible
 zinc-finger. Not a homolog of the archaeal RadA protein.
XX
# Revision 1.6 2023/06/01
//