AC   MF_01645;
DC   Protein; auto
TR   HAMAP; MF_01645; -; 1; level=0
XX
Names: Hydantoinase
XX
ID   ALLB
DE   RecName: Full=Allantoinase;
DE            EC=3.5.2.5;
DE   AltName: Full=Allantoin-utilizing enzyme;
case <OC:Bacillus>
GN   Name=allB; Synonyms=pucH;
else
GN   Name=allB;
end case
XX
CC   -!- FUNCTION: Catalyzes the conversion of allantoin (5-ureidohydantoin) to
CC       allantoic acid by hydrolytic cleavage of the five-member hydantoin
CC       ring.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-allantoin + H2O = allantoate + H(+); Xref=Rhea:RHEA:17029,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15678,
CC         ChEBI:CHEBI:17536; EC=3.5.2.5;
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 2 Zn(2+) ions per subunit.;
CC   -!- PATHWAY: Nitrogen metabolism; (S)-allantoin degradation; allantoate
CC       from (S)-allantoin: step 1/1.
CC   -!- SUBUNIT: Homotetramer.
CC   -!- PTM: Carboxylation allows a single lysine to coordinate two zinc ions.
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Allantoinase family.
XX
DR   Pfam; PF01979; Amidohydro_1; 1; trigger=no
DR   NCBIfam; TIGR00857; PyrC_multi; 1; trigger=no
XX
KW   Hydrolase
KW   Metal-binding
KW   Purine metabolism
KW   Zinc
XX
GO   GO:0004038; F:allantoinase activity
GO   GO:0000256; P:allantoin catabolic process
XX
FT   From: ALLB_ECOLI (P77671)
FT   BINDING         59
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT   Condition: H
FT   BINDING         61
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT   Condition: H
FT   BINDING         146
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /note="via carbamate group"
FT   Condition: K
FT   BINDING         146
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /note="via carbamate group"
FT   Condition: K
FT   BINDING         186
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT   Condition: H
FT   BINDING         242
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT   Condition: H
FT   BINDING         315
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT   Condition: D
FT   MOD_RES         146
FT                   /note="N6-carboxylysine"
FT   Condition: K
XX
Size: 438-457;
Related: None;
Template: P77671; O32137;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: in DEIGD
Comments: None
XX
# Revision 1.28 2023/06/01
//