AC   MF_01674;
DC   Protein; auto
TR   HAMAP; MF_01674; -; 1; level=0
XX
Names: Sep_tRNA_synth
XX
ID   SEPS
DE   RecName: Full=O-phosphoserine--tRNA(Cys) ligase;
DE            Short=O-phosphoserine--tRNA ligase;
DE            EC=6.1.1.27;
DE   AltName: Full=Non-canonical O-phosphoseryl-tRNA(Cys) synthetase;
DE   AltName: Full=O-phosphoseryl-tRNA(Cys) synthetase;
DE            Short=SepRS;
GN   Name=sepS;
XX
CC   -!- FUNCTION: Catalyzes the attachment of O-phosphoserine (Sep) to
CC       tRNA(Cys).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + O-phospho-L-serine + tRNA(Cys) = AMP + diphosphate + O-
CC         phospho-L-seryl-tRNA(Cys); Xref=Rhea:RHEA:25678, Rhea:RHEA-COMP:9661,
CC         Rhea:RHEA-COMP:9719, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:57524, ChEBI:CHEBI:78442, ChEBI:CHEBI:78551,
CC         ChEBI:CHEBI:456215; EC=6.1.1.27;
CC   -!- SUBUNIT: Homotetramer. Interacts with SepCysS.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       O-phosphoseryl-tRNA(Cys) synthetase subfamily.
XX
DR   PROSITE; PS50862; AA_TRNA_LIGASE_II; 1; trigger=no
DR   Pfam; PF01409; tRNA-synt_2d; 2; trigger=no
DR   NCBIfam; TIGR00470; SepS; 1; trigger=no
XX
KW   Aminoacyl-tRNA synthetase
KW   ATP-binding
KW   Ligase
KW   Nucleotide-binding
KW   Protein biosynthesis
XX
GO   GO:0004812; F:aminoacyl-tRNA ligase activity
GO   GO:0005524; F:ATP binding
GO   GO:0043039; P:tRNA aminoacylation
XX
FT   From: SEPS_ARCFU (O30126)
FT   BINDING         186..188
FT                   /ligand="substrate"
FT   Condition: H-M-T
FT   BINDING         231..233
FT                   /ligand="substrate"
FT   Condition: S-A-S
FT   BINDING         273..274
FT                   /ligand="substrate"
FT   Condition: Y-Y
FT   BINDING         325
FT                   /ligand="substrate"
FT   Condition: N
XX
Size: 526-562;
Related: None;
Template: Q59054; O30126;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.13 2023/06/01
//