AC   MF_01683;
DC   Protein; auto
TR   HAMAP; MF_01683; -; 1; level=0
XX
Names: Salvage_MtnK
XX
ID   MTNK
DE   RecName: Full=Methylthioribose kinase;
DE            Short=MTR kinase;
DE            EC=2.7.1.100;
GN   Name=mtnK;
XX
CC   -!- FUNCTION: Catalyzes the phosphorylation of methylthioribose into
CC       methylthioribose-1-phosphate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-(methylsulfanyl)-D-ribose + ATP = ADP + H(+) + S-methyl-5-
CC         thio-alpha-D-ribose 1-phosphate; Xref=Rhea:RHEA:22312,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:58533,
CC         ChEBI:CHEBI:78440, ChEBI:CHEBI:456216; EC=2.7.1.100;
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via salvage
CC       pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-
CC       thioadenosine (hydrolase route): step 2/2.
CC   -!- SUBUNIT: Homodimer.
CC   -!- SIMILARITY: Belongs to the methylthioribose kinase family.
XX
DR   Pfam; PF01636; APH; 1; trigger=no
DR   PIRSF; PIRSF031134; MTRK; 1; trigger=no
DR   NCBIfam; TIGR01767; MTRK; 1; trigger=no
XX
KW   Amino-acid biosynthesis
KW   ATP-binding
KW   Kinase
KW   Methionine biosynthesis
KW   Nucleotide-binding
KW   Transferase
XX
GO   GO:0005524; F:ATP binding
GO   GO:0046522; F:S-methyl-5-thioribose kinase activity
GO   GO:0019284; P:L-methionine salvage from S-adenosylmethionine
XX
FT   From: MTNK_BACSU (O31663)
FT   BINDING         115..117
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: E-D-L
FT   BINDING         250..252
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: D-[AP]-E
FT   BINDING         44
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: N
FT   BINDING         61
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: K
FT   BINDING         233
FT                   /ligand="substrate"
FT   Condition: D
FT   BINDING         340
FT                   /ligand="substrate"
FT   Condition: R
XX
Size: 389-407;
Related: None;
Template: O31663; Q9F0P1;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.17 2023/06/01
//