AC   MF_01696;
DC   Protein; auto
TR   HAMAP; MF_01696; -; 1; level=0
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Names: MshB
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ID   MSHB
DE   RecName: Full=1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase;
DE            Short=GlcNAc-Ins deacetylase;
DE            EC=3.5.1.103;
DE   AltName: Full=N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase;
GN   Name=mshB;
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CC   -!- FUNCTION: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-
CC       deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol
CC       biosynthesis pathway.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside +
CC         H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside +
CC         acetate; Xref=Rhea:RHEA:26180, ChEBI:CHEBI:15377, ChEBI:CHEBI:30089,
CC         ChEBI:CHEBI:52442, ChEBI:CHEBI:58886; EC=3.5.1.103;
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 1 zinc ion per subunit.;
CC   -!- SIMILARITY: Belongs to the MshB deacetylase family.
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DR   Pfam; PF02585; PIG-L; 1; trigger=no
DR   NCBIfam; TIGR03445; Mycothiol_MshB; 1; trigger=no
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KW   Hydrolase
KW   Metal-binding
KW   Zinc
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GO   GO:0008270; F:zinc ion binding
GO   GO:0019213; F:deacetylase activity
GO   GO:0010125; P:mycothiol biosynthetic process
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FT   From: MSHB_MYCTU (P9WJN3)
FT   BINDING         13
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Condition: H
FT   BINDING         16
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Condition: D
FT   BINDING         147
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Condition: H
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Size: 230-426;
Related: MF_01482;
Template: A0R2I7; P9WJN3;
Scope:
 Bacteria; Actinomycetota
Fusion:
 Nter: None
 Cter: None
Duplicate: in CATAD, FRAAA, FRACC, SACEN
Plasmid: None
Comments: None
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# Revision 1.15 2023/06/01
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