AC MF_01817; DC Protein; auto TR HAMAP; MF_01817; -; 1; level=0 XX Names: Recomb_XerD_like XX ID XERDL DE RecName: Full=Tyrosine recombinase XerD-like; XX CC -!- FUNCTION: Putative tyrosine recombinase. Not involved in the cutting CC and rejoining of the recombining DNA molecules on dif(SL) site. CC -!- SUBCELLULAR LOCATION: Cytoplasm. CC -!- SIMILARITY: Belongs to the 'phage' integrase family. XerD-like CC subfamily. XX DR Pfam; PF00589; Phage_integrase; 1; trigger=no DR Pfam; PF02899; Phage_integr_N; 1; trigger=no DR PROSITE; PS51900; CB; 1; trigger=yes DR PROSITE; PS51898; TYR_RECOMBINASE; 1; trigger=yes XX KW Cytoplasm KW DNA recombination KW DNA integration KW DNA-binding XX GO GO:0009037; F:tyrosine-based site-specific recombinase activity GO GO:0006310; P:DNA recombination GO GO:0006313; P:DNA transposition GO GO:0005737; C:cytoplasm XX FT From: XERDL_LACLA (Q9CG32) FT ACT_SITE 236 FT /note="O-(3'-phospho-DNA)-tyrosine intermediate" FT Condition: Y XX Size: 238-253; Related: None; Template: P0A4T0; Q9CG32; Scope: Bacteria; Streptococcaceae Fusion: Nter: None Cter: None Duplicate: None Plasmid: None Comments: Although strongly related to XerD, it constitutes a distinct protein family. In contrast to the classic XerD protein, it does not contain the Arg-His-Arg-His (R-H-R-H) sandwich residues that are clustered with the Tyr active site. It also lacks the C-terminal region which is known to mediate the interaction with XerC. It is therefore unknown whether it has tyrosine recombinase activity or acts as a regulator. XX # Revision 1.26 2023/03/27 //