AC MF_01818; DC Protein; auto TR HAMAP; MF_01818; -; 1; level=0 XX Names: RNase_Z_BN XX case ID RBN DE RecName: Full=Ribonuclease BN; DE Short=RNase BN; DE EC=3.1.-.-; DE AltName: Full=Ribonuclease Z homolog; DE Short=RNase Z homolog; GN Name=rbn; else ID RNZ DE RecName: Full=Ribonuclease Z; DE Short=RNase Z; DE EC=3.1.26.11; DE AltName: Full=tRNA 3 endonuclease; DE AltName: Full=tRNase Z; GN Name=rnz; end case XX case CC -!- FUNCTION: Zinc phosphodiesterase, which has both exoribonuclease and CC endoribonuclease activities. else CC -!- FUNCTION: Zinc phosphodiesterase, which displays some tRNA 3'- CC processing endonuclease activity. Probably involved in tRNA maturation, CC by removing a 3'-trailer from precursor tRNA. CC -!- CATALYTIC ACTIVITY: CC Reaction=Endonucleolytic cleavage of RNA, removing extra 3' nucleotides CC from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy CC group is left at the tRNA terminus and a 5'-phosphoryl group is left CC at the trailer molecule.; EC=3.1.26.11; end case case CC -!- COFACTOR: CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; CC Note=Binds 2 Zn(2+) ions.; end case CC -!- SUBUNIT: Homodimer. case CC -!- SIMILARITY: Belongs to the RNase Z family. RNase BN subfamily. else CC -!- SIMILARITY: Belongs to the RNase Z family. end case XX DR Pfam; PF00753; Lactamase_B; 1; trigger=no DR NCBIfam; TIGR02651; RNase_Z; 1; trigger=no DR NCBIfam; TIGR02649; True_RNase_BN; 1; trigger=no XX KW tRNA processing KW Hydrolase KW Nuclease KW Endonuclease case KW Exonuclease end case case KW Metal-binding KW Zinc end case XX case GO GO:0008270; F:zinc ion binding end case case GO GO:0004519; F:endonuclease activity GO GO:0004527; F:exonuclease activity else GO GO:0042781; F:3'-tRNA processing endoribonuclease activity end case GO GO:0008033; P:tRNA processing XX FT From: RNZ_BACSU (P54548) FT ACT_SITE 67 FT /note="Proton acceptor" FT Condition: D FT BINDING 63 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="1" FT /ligand_note="catalytic" FT Group: 1; Condition: H FT BINDING 65 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="1" FT /ligand_note="catalytic" FT Group: 1; Condition: H FT BINDING 67 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="2" FT /ligand_note="catalytic" FT Group: 1; Condition: D FT BINDING 68 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="2" FT /ligand_note="catalytic" FT Group: 1; Condition: H FT BINDING 140 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="1" FT /ligand_note="catalytic" FT Group: 1; Condition: H FT BINDING 211 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="1" FT /ligand_note="catalytic" FT Group: 1; Condition: D FT BINDING 211 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="2" FT /ligand_note="catalytic" FT Group: 1; Condition: D FT BINDING 269 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="2" FT /ligand_note="catalytic" FT Group: 1; Condition: H XX Size: 220-407; Related: None; Template: P0A8V0; Q58897; P54548; Scope: Bacteria Archaea Fusion: Nter: None Cter: Duplicate: None Plasmid: None Comments: Was initially thought to be an arylsulfatase, given its similarity with the atsA family. XX # Revision 1.26 2023/06/01 //