AC   MF_01820;
DC   Protein; auto
TR   HAMAP; MF_01820; -; 1; level=0
XX
Names: GTPase_RsgA
XX
ID   RSGA
DE   RecName: Full=Small ribosomal subunit biogenesis GTPase RsgA;
DE            EC=3.6.1.-;
GN   Name=rsgA;
XX
CC   -!- FUNCTION: One of several proteins that assist in the late maturation
CC       steps of the functional core of the 30S ribosomal subunit. Helps
CC       release RbfA from mature subunits. May play a role in the assembly of
CC       ribosomal proteins into the subunit. Circularly permuted GTPase that
CC       catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S
CC       ribosomal subunit.
case <FTGroup:1>
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 1 zinc ion per subunit.;
end case
CC   -!- SUBUNIT: Monomer. Associates with 30S ribosomal subunit, binds 16S
CC       rRNA.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA
CC       subfamily.
XX
DR   Pfam; PF03193; DUF258; 1; trigger=no
DR   NCBIfam; TIGR00157; TIGR00157; 1; trigger=no
DR   PROSITE; PS50936; ENGC_GTPASE; 1; trigger=no
DR   PROSITE; PS51721; G_CP; 1; trigger=yes
XX
KW   Cytoplasm
KW   Hydrolase
KW   GTP-binding
KW   Nucleotide-binding
KW   Ribosome biogenesis
KW   RNA-binding
KW   rRNA-binding
case <FTGroup:1>
KW   Zinc
KW   Metal-binding
end case
XX
GO   GO:0003924; F:GTPase activity
GO   GO:0005525; F:GTP binding
GO   GO:0005737; C:cytoplasm
GO   GO:0042274; P:ribosomal small subunit biogenesis
XX
FT   From: RSGA_SALTY (Q8ZKB0)
FT   BINDING         160..163
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT   Condition: [NTSA]-K-x-D
FT   BINDING         214..222
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT   Condition: [AG]-x(4)-G-K-[ST]-[TS]
FT   BINDING         297
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         302
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
FT   BINDING         304
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: H
FT   BINDING         310
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: C
XX
Size: 272-387;
Related: None;
Template: P39286; Q9X242;
Scope:
 Bacteria
 Archaea; Methanosarcinales
Fusion:
 Nter: None
 Cter: None
Duplicate: in NOSS1, BACTN, LACPL, LISIN, LISMO, OCEIH, VIBPA, VIBVU
Plasmid: in NOSS1
Comments: In contrast to most P-loop GTPases, which have a G1-G2-G3-G4
 pattern of GTP-binding motifs, contains a permuted G4-G1-G2-G3 pattern.
 Often referred to as YjeQ.
XX
# Revision 1.32 2023/06/01
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