AC   MF_01857;
DC   Protein; auto
TR   HAMAP; MF_01857; -; 1; level=0
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Names: 23SrRNA_methyltr_I
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ID   RLMI
DE   RecName: Full=Ribosomal RNA large subunit methyltransferase I;
DE            EC=2.1.1.191;
DE   AltName: Full=23S rRNA m5C1962 methyltransferase;
DE   AltName: Full=rRNA (cytosine-C(5)-)-methyltransferase RlmI;
GN   Name=rlmI;
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CC   -!- FUNCTION: Specifically methylates the cytosine at position 1962
CC       (m5C1962) of 23S rRNA.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=cytidine(1962) in 23S rRNA + S-adenosyl-L-methionine = 5-
CC         methylcytidine(1962) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:42912, Rhea:RHEA-COMP:10382, Rhea:RHEA-COMP:10386,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:74483, ChEBI:CHEBI:82748; EC=2.1.1.191;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmI family.
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DR   PROSITE; PS50890; PUA; 1; trigger=yes
DR   Pfam; PF03602; Cons_hypoth95; 1; trigger=no
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KW   Cytoplasm
KW   Methyltransferase
KW   RNA-binding
KW   rRNA processing
KW   S-adenosyl-L-methionine
KW   Transferase
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GO   GO:0016434; F:rRNA (cytosine) methyltransferase activity
GO   GO:0031167; P:rRNA methylation
GO   GO:0005737; C:cytoplasm
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FT   None
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Size: 394-403;
Related: None;
Template: P75876;
Scope:
 Bacteria; Gammaproteobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: The family is restricted to Gammaproteobacteria in order to avoid wrong matches.
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# Revision 1.8 2019/11/19
//