AC   MF_01881;
DC   Protein; auto
TR   HAMAP; MF_01881; -; 1; level=0
XX
Names: Propion_kin_subfam1
XX
ID   TDCD
DE   RecName: Full=Propionate kinase;
DE            EC=2.7.2.15;
GN   Name=tdcD;
XX
CC   -!- FUNCTION: Catalyzes the conversion of propionyl phosphate and ADP to
CC       propionate and ATP.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + propanoate = ADP + propanoyl phosphate;
CC         Xref=Rhea:RHEA:23148, ChEBI:CHEBI:17272, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:58933, ChEBI:CHEBI:456216; EC=2.7.2.15;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC   -!- PATHWAY: Amino-acid degradation; L-threonine degradation via propanoate
CC       pathway; propanoate from L-threonine: step 4/4.
CC   -!- SUBUNIT: Homodimer.
CC   -!- SIMILARITY: Belongs to the acetokinase family. TdcD subfamily.
XX
DR   Pfam; PF00871; Acetate_kinase; 1; trigger=no
DR   PRINTS; PR00471; ACETATEKNASE; 1; trigger=no
DR   NCBIfam; TIGR00016; AckA; 1; trigger=no
DR   PIRSF; PIRSF000722; Acetate_prop_kin; 1; trigger=no
DR   PROSITE; PS01075; ACETATE_KINASE_1; 1; trigger=no
DR   PROSITE; PS01076; ACETATE_KINASE_2; 1; trigger=no
XX
KW   ATP-binding
KW   Kinase
KW   Magnesium
KW   Metal-binding
KW   Nucleotide-binding
KW   Transferase
XX
GO   GO:0008980; F:propionate kinase activity
GO   GO:0016310; P:phosphorylation
XX
FT   From: TDCD_SALTY (O06961)
FT   BINDING         203..207
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: H-L-G-N-G
FT   BINDING         278..280
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: D-[LM]-R
FT   BINDING         326..330
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: G-I-G-E-N
FT   ACT_SITE        143
FT                   /note="Proton donor/acceptor"
FT   Condition: D
FT   BINDING         11
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: N
FT   BINDING         381
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: D
FT   BINDING         11
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: N
FT   BINDING         18
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: K
FT   BINDING         86
FT                   /ligand="substrate"
FT   Condition: R
FT   BINDING         175
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: H
FT   BINDING         326
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Condition: G
FT   SITE            175
FT                   /note="Transition state stabilizer"
FT   Condition: H
FT   SITE            236
FT                   /note="Transition state stabilizer"
FT   Condition: R
XX
Size: 372-418;
Related: MF_00020;
Template: P11868; O06961;
Scope:
 Bacteria; Enterobacterales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.14 2023/06/01
//