AC MF_01884; DC Protein; auto TR HAMAP; MF_01884; -; 1; level=0 XX Names: Rho XX ID RHO DE RecName: Full=Transcription termination factor Rho; DE EC=3.6.4.-; DE AltName: Full=ATP-dependent helicase Rho; GN Name=rho; XX CC -!- FUNCTION: Facilitates transcription termination by a mechanism that CC involves Rho binding to the nascent RNA, activation of Rho's RNA- CC dependent ATPase activity, and release of the mRNA from the DNA CC template. CC -!- SUBUNIT: Homohexamer. The homohexamer assembles into an open ring CC structure. CC -!- SIMILARITY: Belongs to the Rho family. XX DR Pfam; PF00006; ATP-synt_ab; 1; trigger=no DR Pfam; PF07498; Rho_N; 1; trigger=no DR Pfam; PF07497; Rho_RNA_bind; 1; trigger=no DR NCBIfam; TIGR00767; Rho; 1; trigger=no DR PROSITE; PS51856; RHO_RNA_BD; 1; trigger=yes XX KW ATP-binding KW Helicase KW Hydrolase KW Nucleotide-binding KW RNA-binding KW Transcription KW Transcription regulation KW Transcription termination XX GO GO:0005524; F:ATP binding GO GO:0004386; F:helicase activity GO GO:0003723; F:RNA binding GO GO:0006353; P:DNA-templated transcription termination XX FT From: RHO_ECOLI (P0AG30) FT BINDING 169..174 FT /ligand="ATP" FT /ligand_id="ChEBI:CHEBI:30616" FT Condition: G-x-G-x-x-[GAS] FT BINDING 181..186 FT /ligand="ATP" FT /ligand_id="ChEBI:CHEBI:30616" FT Condition: [KR]-x-G-K-[TS]-x FT REGION 61..66 FT /note="RNA-binding 1" FT Optional; Group: 1; Condition: G-[FY]-G-[FYR]-[LV]-R FT REGION 78..80 FT /note="RNA-binding 1" FT Optional; Group: 1; Condition: D-I-[YFR] FT REGION 108..110 FT /note="RNA-binding 1" FT Optional; Group: 1; Condition: [ED]-R-[YFR] FT REGION 284..288 FT /note="RNA-binding 2" FT Optional; Group: 1; Condition: [VL]-L-[TS]-G-G FT BINDING 212 FT /ligand="ATP" FT /ligand_id="ChEBI:CHEBI:30616" FT Condition: R FT SITE 326 FT /note="RNA-binding 2" FT Optional; Group: 1; Condition: K XX Size: 341-849; Related: None; Template: P0AG30; Scope: Bacteria Fusion: Nter: None Cter: None Duplicate: in EHRCR Plasmid: None Comments: None XX # Revision 1.14 2023/06/01 //