AC   MF_01924;
DC   Protein; auto
TR   HAMAP; MF_01924; -; 1; level=0
XX
Names: A_A_dipeptidase
XX
ID   DDPX
DE   RecName: Full=D-alanyl-D-alanine dipeptidase;
DE            Short=D-Ala-D-Ala dipeptidase;
DE            EC=3.4.13.22;
case <OC:Pseudomonadota>
GN   Name=ddpX;
end case
XX
CC   -!- FUNCTION: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-alanyl-D-alanine + H2O = 2 D-alanine; Xref=Rhea:RHEA:20661,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:57416, ChEBI:CHEBI:57822;
CC         EC=3.4.13.22;
case <FTGroup:1>
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 1 zinc ion per subunit.;
end case
CC   -!- SIMILARITY: Belongs to the peptidase M15D family.
XX
DR   Pfam; PF01427; Peptidase_M15; 1; trigger=no
DR   PIRSF; PIRSF026671; AA_dipeptidase; 1; trigger=no
XX
KW   Dipeptidase
KW   Hydrolase
KW   Metalloprotease
KW   Protease
case <FTGroup:1>
KW   Metal-binding
KW   Zinc
end case
XX
GO   GO:0016805; F:dipeptidase activity
case <FTGroup:1>
GO   GO:0008270; F:zinc ion binding
end case
XX
FT   From: VANX_ENTFC (Q06241)
FT   ACT_SITE        181
FT                   /note="Proton donor/acceptor"
FT   Condition: E
FT   BINDING         116
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: H
FT   BINDING         123
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: D
FT   BINDING         184
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: H
FT   SITE            71
FT                   /note="Transition state stabilizer"
FT   Condition: R
XX
Size: 169-330;
Related: None;
Template: Q06241; P77790; P74268; Q9XAK6;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: in ENTFC
Comments: None
XX
# Revision 1.8 2023/01/26
//