AC MF_01937; DC Protein; auto TR HAMAP; MF_01937; -; 1; level=0 XX Names: MenA_1 XX ID MENA DE RecName: Full=1,4-dihydroxy-2-naphthoate octaprenyltransferase; DE Short=DHNA-octaprenyltransferase; DE EC=2.5.1.74; GN Name=menA; XX CC -!- FUNCTION: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to CC demethylmenaquinone (DMK). CC -!- CATALYTIC ACTIVITY: CC Reaction=1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl CC diphosphate + H(+) = a 2-demethylmenaquinol + CO2 + diphosphate; CC Xref=Rhea:RHEA:26478, Rhea:RHEA-COMP:9563, Rhea:RHEA-COMP:9564, CC ChEBI:CHEBI:11173, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, CC ChEBI:CHEBI:33019, ChEBI:CHEBI:55437, ChEBI:CHEBI:58914; EC=2.5.1.74; CC -!- PATHWAY: Quinol/quinone metabolism; menaquinone biosynthesis; CC menaquinol from 1,4-dihydroxy-2-naphthoate: step 1/2. case not defined or CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. else case CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein. end case CC -!- SIMILARITY: Belongs to the MenA family. Type 1 subfamily. XX DR Pfam; PF01040; UbiA; 1; trigger=no DR NCBIfam; TIGR00751; menA; 1; trigger=no DR PIRSF; PIRSF005355; UBIAD1; 1; trigger=no DR General; Transmembrane; -; 6-9; trigger=yes XX case defined and KW Cell inner membrane end case KW Cell membrane KW Membrane KW Menaquinone biosynthesis KW Transferase KW Transmembrane KW Transmembrane helix XX GO GO:0046428; F:1,4-dihydroxy-2-naphthoate octaprenyltransferase activity GO GO:0009234; P:menaquinone biosynthetic process GO GO:0005886; C:plasma membrane XX FT None XX Size: 275-360; Related: None; Template: P32166; Scope: Bacteria Archaea Fusion: Nter: None Cter: None Duplicate: None Plasmid: None Comments: None XX # Revision 1.6 2023/06/01 //