AC MF_01938; DC Protein; auto TR HAMAP; MF_01938; -; 1; level=0 XX Names: MenA_2 XX ID MENA DE RecName: Full=2-carboxy-1,4-naphthoquinone phytyltransferase; DE EC=2.5.1.130; DE AltName: Full=1,4-dihydroxy-2-naphthoate phytyltransferase; DE Short=DHNA phytyltransferase; GN Name=menA; XX CC -!- FUNCTION: Involved in the synthesis of phylloquinone (vitamin K1). CC Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- CC naphthoquinone. CC -!- CATALYTIC ACTIVITY: CC Reaction=1,4-dioxo-2-naphthoate + H(+) + phytyl diphosphate = CO2 + CC demethylphylloquinone + diphosphate; Xref=Rhea:RHEA:47740, CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:31087, CC ChEBI:CHEBI:33019, ChEBI:CHEBI:75434, ChEBI:CHEBI:87842; CC EC=2.5.1.130; CC -!- PATHWAY: Cofactor biosynthesis; phylloquinone biosynthesis. CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein. CC -!- SIMILARITY: Belongs to the MenA family. Type 2 subfamily. XX DR Pfam; PF01040; UbiA; 1; trigger=no DR NCBIfam; TIGR02235; menA_cyano-plnt; 1; trigger=no DR PIRSF; PIRSF005355; UBIAD1; 1; trigger=no DR General; Transmembrane; -; 7-9; trigger=yes XX KW Cell inner membrane KW Cell membrane KW Membrane KW Transferase KW Transmembrane KW Transmembrane helix XX GO GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups GO GO:0042372; P:phylloquinone biosynthetic process GO GO:0005886; C:plasma membrane XX FT None XX Size: 277-340; Related: None; Template: P73962; Scope: Bacteria; Cyanobacteriota Fusion: Nter: None Cter: None Duplicate: None Plasmid: None Comments: None XX # Revision 1.7 2023/06/01 //