AC   MF_01952;
DC   Protein; auto
TR   HAMAP; MF_01952; -; 1; level=0
XX
Names: UlaF
XX
ID   ULAF
case <FTGroup:1>
DE   RecName: Full=L-ribulose-5-phosphate 4-epimerase UlaF;
DE            EC=5.1.3.4;
DE   AltName: Full=L-ascorbate utilization protein F;
DE   AltName: Full=Phosphoribulose isomerase;
end case
case not <FTGroup:1>
DE   RecName: Full=Putative L-ribulose-5-phosphate 4-epimerase;
end case
GN   Name=ulaF;
XX
CC   -!- FUNCTION: Catalyzes the isomerization of L-ribulose 5-phosphate to D-
CC       xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate
CC       utilization.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-ribulose 5-phosphate = D-xylulose 5-phosphate;
CC         Xref=Rhea:RHEA:22368, ChEBI:CHEBI:57737, ChEBI:CHEBI:58226;
CC         EC=5.1.3.4;
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 1 zinc ion per subunit.;
CC   -!- PATHWAY: Cofactor degradation; L-ascorbate degradation; D-xylulose 5-
CC       phosphate from L-ascorbate: step 4/4.
CC   -!- INDUCTION: Induced by L-ascorbate. Repressed by UlaR.
CC   -!- SIMILARITY: Belongs to the aldolase class II family. AraD/FucA
CC       subfamily.
XX
DR   Pfam; PF00596; Aldolase_II; 1; trigger=no
XX
KW   Carbohydrate metabolism
KW   Isomerase
KW   Metal-binding
KW   Zinc
XX
GO   GO:0019852; P:L-ascorbic acid metabolic process
GO   GO:0008742; F:L-ribulose-phosphate 4-epimerase activity
GO   GO:0008270; F:zinc ion binding
XX
FT   From: ULAF_ECOLI (P39306)
FT   BINDING         26..27
FT                   /ligand="substrate"
FT   Condition: G-N
FT   BINDING         43..44
FT                   /ligand="substrate"
FT   Condition: [TS]-G
FT   BINDING         72..73
FT                   /ligand="substrate"
FT   Condition: S-S
FT   ACT_SITE        118
FT                   /note="Proton donor/acceptor"
FT   Condition: D
FT   ACT_SITE        225
FT                   /note="Proton donor/acceptor"
FT   Condition: Y
FT   BINDING         74
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: D
FT   BINDING         93
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: H
FT   BINDING         95
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: H
FT   BINDING         167
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT   Group: 1; Condition: H
XX
Size: 228-228;
Related: None;
Template: P39306;
Scope:
 Bacteria; Enterobacteriaceae
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.23 2022/11/19
//