AC   MF_02026;
DC   Protein; auto
TR   HAMAP; MF_02026; -; 1; level=0
XX
Names: WecE_RffA
XX
ID   WECE
DE   RecName: Full=dTDP-4-amino-4,6-dideoxygalactose transaminase;
DE            EC=2.6.1.59;
GN   Name=wecE;
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CC   -!- FUNCTION: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-
CC       galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-
CC       Glc4O) and L-glutamate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose =
CC         dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate;
CC         Xref=Rhea:RHEA:10368, ChEBI:CHEBI:16810, ChEBI:CHEBI:29985,
CC         ChEBI:CHEBI:57649, ChEBI:CHEBI:68492; EC=2.6.1.59;
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; enterobacterial common
CC       antigen biosynthesis.
CC   -!- SIMILARITY: Belongs to the DegT/DnrJ/EryC1 family.
XX
DR   Pfam; PF01041; DegT_DnrJ_EryC1; 1; trigger=no
DR   NCBIfam; TIGR02379; ECA_wecE; 1; trigger=no
DR   PIRSF; PIRSF000390; PLP_StrS; 1; trigger=no
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KW   Pyridoxal phosphate
KW   Transferase
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GO   GO:0019180; F:dTDP-4-amino-4,6-dideoxygalactose transaminase activity
GO   GO:0030170; F:pyridoxal phosphate binding
GO   GO:0009246; P:enterobacterial common antigen biosynthetic process
XX
FT   From: WECE_ECOLI (P27833)
FT   MOD_RES         181
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT   Condition: K
XX
Size: 360-392;
Related: None;
Template: P27833;
Scope:
 Bacteria; Enterobacterales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.7 2023/06/01
//