AC   MF_02046;
DC   Protein; auto
TR   HAMAP; MF_02046; -; 1; level=0
XX
Names: Glc6PDH_archaea
XX
ID   G6PD
DE   RecName: Full=NAD-dependent glucose-6-phosphate dehydrogenase;
DE            Short=Glc6PDH;
DE            EC=1.1.1.388;
XX
CC   -!- FUNCTION: Catalyzes the NAD-dependent oxidation of glucose 6-phosphate
CC       to 6-phosphogluconolactone.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-glucose 6-phosphate + NAD(+) = 6-phospho-D-glucono-1,5-
CC         lactone + H(+) + NADH; Xref=Rhea:RHEA:38215, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:57955,
CC         ChEBI:CHEBI:61548; EC=1.1.1.388;
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway.
CC   -!- SUBUNIT: Homodimer.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family.
XX
DR   Pfam; PF01370; Epimerase; 1; trigger=no
XX
KW   Carbohydrate metabolism
KW   Glucose metabolism
KW   NAD
KW   Oxidoreductase
XX
GO   GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO   GO:0051287; F:NAD binding
GO   GO:0009051; P:pentose-phosphate shunt, oxidative branch
XX
FT   From: G6PD_HALVD (D4GS48)
FT   ACT_SITE        152
FT                   /note="Proton acceptor"
FT   Condition: Y
FT   BINDING         90
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT   Optional; Condition: N
FT   BINDING         115
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT   Optional; Condition: S
FT   BINDING         152
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT   Optional; Condition: Y
FT   BINDING         156
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT   Optional; Condition: K
XX
Size: 230-310;
Related: None;
Template: D4GS48;
Scope:
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.6 2024/01/25
//