AC   MF_02052;
DC   Protein; auto
TR   HAMAP; MF_02052; -; 1; level=0
XX
Names: LsrF
XX
ID   LSRF
DE   RecName: Full=3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase;
DE            EC=2.3.1.245;
GN   Name=lsrF;
XX
CC   -!- FUNCTION: Involved in the degradation of phospho-AI-2, thereby
CC       terminating induction of the lsr operon and closing the AI-2 signaling
CC       cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-
CC       phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and
CC       acetyl-CoA.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + dihydroxyacetone phosphate = 3-hydroxy-2,4-
CC         dioxopentyl phosphate + CoA; Xref=Rhea:RHEA:44736, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57288, ChEBI:CHEBI:57642, ChEBI:CHEBI:84359;
CC         EC=2.3.1.245;
CC   -!- SUBUNIT: Homodecamer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the DeoC/FbaB aldolase family.
XX
DR   Pfam; PF01791; DeoC; 1; trigger=no
DR   PIRSF; PIRSF038992; Aldolase_Ia; 1; trigger=no
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KW   Cytoplasm
KW   Schiff base
KW   Transferase
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GO   GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups
GO   GO:0005737; C:cytoplasm
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FT   From: LSRF_ECOLI (P76143)
FT   ACT_SITE        203
FT                   /note="Schiff-base intermediate with substrate"
FT   Condition: K
XX
Size: 290-310;
Related: None;
Template: P76143;
Scope:
 Bacteria; Enterobacterales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.6 2021/06/04
//