AC   MF_02053;
DC   Protein; auto
TR   HAMAP; MF_02053; -; 1; level=0
XX
Names: LsrK
XX
ID   LSRK
DE   RecName: Full=Autoinducer-2 kinase;
DE            Short=AI-2 kinase;
DE            EC=2.7.1.189;
GN   Name=lsrK;
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CC   -!- FUNCTION: Catalyzes the phosphorylation of autoinducer-2 (AI-2) to
CC       phospho-AI-2, which subsequently inactivates the transcriptional
CC       regulator LsrR and leads to the transcription of the lsr operon.
CC       Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione
CC       (DPD), which is the precursor to all AI-2 signaling molecules, at the
CC       C5 position.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-4,5-dihydroxypentane-2,3-dione + ATP = (2S)-2-hydroxy-3,4-
CC         dioxopentyl phosphate + ADP + H(+); Xref=Rhea:RHEA:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:29484, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:71677, ChEBI:CHEBI:456216; EC=2.7.1.189;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family.
XX
DR   Pfam; PF02782; FGGY_C; 1; trigger=no
DR   Pfam; PF00370; FGGY_N; 1; trigger=no
DR   PIRSF; PIRSF000538; GlpK; 1; trigger=no
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KW   Cytoplasm
KW   Kinase
KW   Transferase
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GO   GO:0071518; F:autoinducer-2 kinase activity
GO   GO:0005737; C:cytoplasm
XX
Size: 515-545;
Related: None;
Template: Q8ZKQ6; P77432;
Scope:
 Bacteria; Enterobacterales
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.5 2020/05/05
//