AC   MF_02057;
DC   Protein; auto
TR   HAMAP; MF_02057; -; 1; level=0
XX
Names: tRNA_methyltr_CmoM
XX
ID   CMOM
DE   RecName: Full=tRNA 5-carboxymethoxyuridine methyltransferase;
DE            EC=2.1.1.-;
DE   AltName: Full=cmo5U methyltransferase;
GN   Name=cmoM;
XX
CC   -!- FUNCTION: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U)
CC       to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in
CC       tRNAs.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-carboxymethoxyuridine(34) in tRNA + S-adenosyl-L-methionine
CC         = 5-methoxycarbonylmethoxyuridine(34) in tRNA + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:54080, Rhea:RHEA-COMP:13383, Rhea:RHEA-
CC         COMP:13781, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:136879,
CC         ChEBI:CHEBI:138053;
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. CmoM family.
XX
DR   Pfam; PF13847; Methyltransf_31; 0-1; trigger=no
DR   Pfam; PF08241; Methyltransf_11; 0-1; trigger=no
XX
KW   Methyltransferase
KW   S-adenosyl-L-methionine
KW   Transferase
KW   tRNA processing
XX
GO   GO:0097697; F:tRNA (5-carboxymethoxyuridine(34)-5-O)-methyltransferase activity
GO   GO:0006400; P:tRNA modification
XX
FT   From: CMOM_ECO57 (Q8XDG3)
FT   BINDING         52..53
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Optional; Condition: G-[GA]
FT   BINDING         102..103
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Optional; Condition: A-Q
FT   BINDING         26
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Optional; Condition: R
FT   BINDING         73
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Optional; Condition: [DE]
FT   BINDING         119
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Optional; Condition: H
XX
Size: 240-320;
Related: None;
Template: P36566; Q8XDG3;
Scope:
 Bacteria; Gammaproteobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.8 2023/10/13
//