AC   MF_02063;
DC   Protein; auto
TR   HAMAP; MF_02063; -; 1; level=0
XX
Names: GltP_subfam
XX
ID   GLTP
case <OC:Enterobacterales>
DE   RecName: Full=Glutamate/aspartate-proton symporter GltP;
else
DE   RecName: Full=Probable glutamate/aspartate-proton symporter GltP;
end case
GN   Name=gltP;
XX
CC   -!- FUNCTION: Catalyzes the proton-dependent transport of glutamate and
CC       aspartate. At least two protons are transported in symport with the
CC       substrate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-glutamate(in) + 2 H(+)(in) = L-glutamate(out) + 2 H(+)(out);
CC         Xref=Rhea:RHEA:29027, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-aspartate(in) + 2 H(+)(in) = L-aspartate(out) + 2 H(+)(out);
CC         Xref=Rhea:RHEA:29287, ChEBI:CHEBI:15378, ChEBI:CHEBI:29991;
CC   -!- SUBUNIT: Homotrimer.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. GltP subfamily.
XX
DR   PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1; trigger=no
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1; trigger=no
DR   Pfam; PF00375; SDF; 1; trigger=no
DR   PRINTS; PR00173; EDTRNSPORT; 1; trigger=no
DR   General; Transmembrane; -; 6-10; trigger=yes
XX
KW   Amino-acid transport
KW   Cell inner membrane
KW   Cell membrane
KW   Membrane
KW   Symport
KW   Transmembrane
KW   Transmembrane helix
KW   Transport
XX
GO   GO:0016020; C:membrane
GO   GO:0005280; F:amino acid:proton symporter activity
GO   GO:0055085; P:transmembrane transport
XX
FT   None
XX
Size: 400-480;
Related: None;
Template: P21345;
Scope:
 Bacteria; Gammaproteobacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Version: 8
# Last updated date: 2025-08-08
# Created date: 2016-04-06
//