AC   MF_02068;
DC   Protein; auto
TR   HAMAP; MF_02068; -; 1; level=0
XX
Names: TarI
XX
ID   TARI
DE   RecName: Full=Ribitol-5-phosphate cytidylyltransferase;
DE            EC=2.7.7.40;
case <OC:Bacilli>
GN   Name=tarI;
end case
XX
CC   -!- FUNCTION: Catalyzes the transfer of the cytidylyl group of CTP to D-
CC       ribitol 5-phosphate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=CTP + D-ribitol 5-phosphate + H(+) = CDP-L-ribitol +
CC         diphosphate; Xref=Rhea:RHEA:12456, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:37563, ChEBI:CHEBI:57608,
CC         ChEBI:CHEBI:57695; EC=2.7.7.40;
case <OC:Bacilli>
CC   -!- PATHWAY: Cell wall biogenesis; poly(ribitol phosphate) teichoic acid
CC       biosynthesis.
end case
CC   -!- SIMILARITY: Belongs to the IspD/TarI cytidylyltransferase family. TarI
CC       subfamily.
XX
DR   PROSITE; PS01295; ISPD; 1; trigger=no
DR   Pfam; PF01128; IspD; 1; trigger=no
XX
KW   Nucleotidyltransferase
KW   Transferase
case <OC:Bacilli>
KW   Cell wall biogenesis/degradation
KW   Teichoic acid biosynthesis
end case
XX
GO   GO:0047349; F:D-ribitol-5-phosphate cytidylyltransferase activity
case <OC:Bacilli>
GO   GO:1902012; P:poly(ribitol phosphate) teichoic acid biosynthetic process
end case
XX
FT   From: TARI_STRR6 (Q8DPI2)
FT   BINDING         7..10
FT                   /ligand="CTP"
FT                   /ligand_id="ChEBI:CHEBI:37563"
FT   Optional; Condition: [LF]-A-G-G
FT   BINDING         82..88
FT                   /ligand="CTP"
FT                   /ligand_id="ChEBI:CHEBI:37563"
FT   Optional; Condition: G-x(3)-[NQ]-x-[ST]
FT   BINDING         113
FT                   /ligand="CTP"
FT                   /ligand_id="ChEBI:CHEBI:37563"
FT   Optional; Condition: S
FT   SITE            14
FT                   /note="Transition state stabilizer"
FT   Condition: R
FT   SITE            22
FT                   /note="Transition state stabilizer"
FT   Condition: K
FT   SITE            161
FT                   /note="Positions ribitol 5-phosphate for the nucleophilic
FT                   attack"
FT   Condition: R
FT   SITE            218
FT                   /note="Positions ribitol 5-phosphate for the nucleophilic
FT                   attack"
FT   Condition: K
XX
Size: 220-260;
Related: None;
Template: Q8DPI2; Q8RKI9; Q2G1C0; Q2G2C4;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in STAA8, STAAB, STAAC, STAAM, STAAN, STAAR, STAAS, STAAW
Plasmid: None
Comments: None
XX
# Revision 1.6 2022/11/19
//