AC   MF_02069;
DC   Protein; auto
TR   HAMAP; MF_02069; -; 1; level=0
XX
Names: TarJ
XX
ID   TARJ
DE   RecName: Full=Ribulose-5-phosphate reductase;
DE            Short=Ribulose-5-P reductase;
DE            EC=1.1.1.405;
DE   AltName: Full=Ribitol-5-phosphate dehydrogenase;
case <OC:Bacilli>
GN   Name=tarJ;
end case
XX
CC   -!- FUNCTION: Catalyzes the NADPH dependent reduction of D-ribulose 5-
CC       phosphate to D-ribitol 5-phosphate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-ribitol 5-phosphate + NADP(+) = D-ribulose 5-phosphate +
CC         H(+) + NADPH; Xref=Rhea:RHEA:19921, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57695, ChEBI:CHEBI:57783, ChEBI:CHEBI:58121,
CC         ChEBI:CHEBI:58349; EC=1.1.1.405;
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
case <OC:Bacilli>
CC   -!- PATHWAY: Cell wall biogenesis; poly(ribitol phosphate) teichoic acid
CC       biosynthesis.
end case
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family.
XX
DR   Pfam; PF08240; ADH_N; 1; trigger=no
DR   Pfam; PF00107; ADH_zinc_N; 1; trigger=no
DR   PROSITE; PS00059; ADH_ZINC; 1; trigger=no
XX
KW   Metal-binding
KW   NADP
KW   Oxidoreductase
KW   Zinc
case <OC:Bacilli>
KW   Cell wall biogenesis/degradation
KW   Teichoic acid biosynthesis
end case
XX
GO   GO:0050256; F:ribitol-5-phosphate 2-dehydrogenase activity
GO   GO:0008270; F:zinc ion binding
case <OC:Bacilli>
GO   GO:1902012; P:poly(ribitol phosphate) teichoic acid biosynthetic process
end case
XX
FT   From: TARJ_STRR6 (Q8DPI3)
FT   BINDING         45
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: C
FT   BINDING         71
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: H
FT   BINDING         72
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: E
FT   BINDING         151
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT   Group: 1; Condition: E
XX
Size: 330-370;
Related: None;
Template: Q8DPI3; Q8RKJ0; Q2G1B9; Q2G1C4;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in STAA8
Plasmid: None
Comments: None
XX
# Revision 1.6 2022/11/19
//