AC   MF_02093;
DC   Protein; auto
TR   HAMAP; MF_02093; -; 1; level=0
XX
Names: Beta_carotene_diox
XX
ID   BLH
DE   RecName: Full=Probable beta-carotene 15,15'-dioxygenase;
DE            EC=1.13.11.63;
XX
CC   -!- FUNCTION: Catalyzes the cleavage of beta-carotene at its central double
CC       bond (15,15') to yield two molecules of all-trans-retinal.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=all-trans-beta-carotene + O2 = 2 all-trans-retinal;
CC         Xref=Rhea:RHEA:32887, ChEBI:CHEBI:15379, ChEBI:CHEBI:17579,
CC         ChEBI:CHEBI:17898; EC=1.13.11.63;
CC   -!- COFACTOR:
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the Brp/Blh beta-carotene diooxygenase family.
XX
DR   Pfam; PF15461; BCD; 1; trigger=no
DR   NCBIfam; TIGR03753; blh_monoox; 1; trigger=no
DR   General; Transmembrane; -; 7-10; trigger=yes
XX
KW   Cell membrane
KW   Dioxygenase
KW   Iron
KW   Membrane
KW   Metal-binding
KW   Oxidoreductase
KW   Transmembrane
KW   Transmembrane helix
XX
GO   GO:0005506; F:iron ion binding
GO   GO:0010436; F:carotenoid dioxygenase activity
GO   GO:0016121; P:carotene catabolic process
GO   GO:0005886; C:plasma membrane
XX
FT   From: BLH_UNCMB (Q4PNI0)
FT   BINDING         21
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT   Optional; Group: 1; Condition: H
FT   BINDING         78
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT   Optional; Group: 1; Condition: H
FT   BINDING         188
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT   Optional; Group: 1; Condition: H
FT   BINDING         192
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT   Optional; Group: 1; Condition: H
XX
Size: 240-390;
Related: None;
Template: Q4PNI0;
Scope:
 Bacteria
 Archaea
Fusion:
 Nter: None
 Cter: None
Duplicate: in HALSA
Plasmid: None
Comments: None
XX
# Revision 1.8 2023/06/01
//