AC   MF_02094;
DC   Protein; auto
TR   HAMAP; MF_02094; -; 1; level=0
XX
Names: Edd
XX
ID   EDD
DE   RecName: Full=Phosphogluconate dehydratase;
DE            EC=4.2.1.12;
GN   Name=edd;
XX
CC   -!- FUNCTION: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-
CC       dehydro-3-deoxy-6-phospho-D-gluconate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-
CC         gluconate + H2O; Xref=Rhea:RHEA:17277, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:57569, ChEBI:CHEBI:58759; EC=4.2.1.12;
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC       Note=Binds 1 [4Fe-4S] cluster
CC   -!- PATHWAY: Carbohydrate metabolism; Entner-Doudoroff pathway.
CC   -!- SIMILARITY: Belongs to the IlvD/Edd family.
XX
DR   PROSITE; PS00886; ILVD_EDD_1; 1; trigger=no
DR   PROSITE; PS00887; ILVD_EDD_2; 1; trigger=no
DR   Pfam; PF00920; ILVD_EDD; 1; trigger=no
DR   NCBIfam; TIGR01196; edd; 1; trigger=no
XX
KW   4Fe-4S
KW   Carbohydrate metabolism
KW   Gluconate utilization
KW   Iron
KW   Iron-sulfur
KW   Lyase
KW   Metal-binding
XX
GO   GO:0004456; F:phosphogluconate dehydratase activity
GO   GO:0051539; F:4 iron, 4 sulfur cluster binding
GO   GO:0046177; P:D-gluconate catabolic process
GO   GO:0009255; P:Entner-Doudoroff pathway through 6-phosphogluconate
XX
FT   From: EDD_ECOLI (P0ADF6)
FT   BINDING         154
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT   Condition: C
FT   BINDING         221
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT   Condition: C
XX
Size: 570-660;
Related: None;
Template: P0ADF6; P21909;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.6 2023/06/01
//