AC   MF_02205;
DC   Protein; auto
TR   HAMAP; MF_02205; -; 1; level=0
XX
Names: DinG_proteobact
XX
ID   DING
DE   RecName: Full=ATP-dependent DNA helicase DinG;
DE            EC=5.6.2.3;
DE   AltName: Full=DNA 5'-3' helicase DinG;
GN   Name=dinG;
XX
CC   -!- FUNCTION: DNA-dependent ATPase and 5'-3' DNA helicase. Unwinds D-loops,
CC       R-loops, forked DNA and G-quadruplex DNA.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA at the
CC         replication fork by translocating in the 5'-3' direction. This
CC         creates two antiparallel DNA single strands (ssDNA). The leading
CC         ssDNA polymer is the template for DNA polymerase III holoenzyme which
CC         synthesizes a continuous strand.; EC=5.6.2.3;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.3;
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC       Note=Binds 1 [4Fe-4S] cluster
CC   -!- SIMILARITY: Belongs to the helicase family. DinG subfamily. Type 1 sub-
CC       subfamily.
XX
DR   PROSITE; PS51193; HELICASE_ATP_BIND_2; 1; trigger=yes
DR   PROSITE; PS51194; HELICASE_CTER; 1; trigger=yes
DR   Pfam; PF00270; DEAD; 1; trigger=no
DR   Pfam; PF06733; DEAD_2; 1; trigger=no
DR   Pfam; PF13307; Helicase_C_2; 1; trigger=no
XX
KW   4Fe-4S
KW   ATP-binding
KW   DNA-binding
KW   Helicase
KW   Hydrolase
KW   Iron
KW   Iron-sulfur
KW   Isomerase
KW   Metal-binding
KW   Nucleotide-binding
XX
GO   GO:0043139; F:5'-3' DNA helicase activity
GO   GO:0005524; F:ATP binding
GO   GO:0003677; F:DNA binding
GO   GO:0051539; F:4 iron, 4 sulfur cluster binding
XX
FT   From: DING_ECOLI (P27296)
FT   BINDING         120
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT   Condition: C
FT   BINDING         194
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT   Condition: C
FT   BINDING         199
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT   Optional; Condition: C
FT   BINDING         205
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT   Condition: C
XX
Size: 650-780;
Related: None;
Template: P27296;
Scope:
 Bacteria; Pseudomonadota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.11 2024/04/22
//