AC   MF_02212;
DC   Protein; auto
TR   HAMAP; MF_02212; -; 1; level=0
XX
Names: Bsr_racemase
XX
ID   BSR
DE   RecName: Full=Broad specificity amino-acid racemase;
DE            EC=5.1.1.10;
DE   Flags: Precursor;
XX
CC   -!- FUNCTION: Amino-acid racemase able to utilize a broad range of
CC       substrates.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an L-alpha-amino acid = a D-alpha-amino acid;
CC         Xref=Rhea:RHEA:18317, ChEBI:CHEBI:59869, ChEBI:CHEBI:59871;
CC         EC=5.1.1.10;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-lysine = D-lysine; Xref=Rhea:RHEA:22864, ChEBI:CHEBI:32551,
CC         ChEBI:CHEBI:32557;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-arginine = D-arginine; Xref=Rhea:RHEA:18069,
CC         ChEBI:CHEBI:32682, ChEBI:CHEBI:32689;
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC   -!- SUBCELLULAR LOCATION: Periplasm.
CC   -!- SIMILARITY: Belongs to the alanine racemase family. Bsr subfamily.
XX
DR   Pfam; PF00842; Ala_racemase_C; 1; trigger=no
DR   Pfam; PF01168; Ala_racemase_N; 1; trigger=no
DR   PRINTS; PR00992; ALARACEMASE; 1; trigger=no
DR   NCBIfam; TIGR00492; alr; 1; trigger=no
DR   PROSITE; PS00395; ALANINE_RACEMASE; 1; trigger=no
DR   General; Signal; -; 1; trigger=yes
XX
KW   Isomerase
KW   Periplasm
KW   Pyridoxal phosphate
KW   Signal
case <FTTag:Disulfide>
KW   Disulfide bond
end case
XX
GO   GO:0047661; F:amino-acid racemase activity
GO   GO:0030170; F:pyridoxal phosphate binding
GO   GO:0042597; C:periplasmic space
XX
FT   From: BSR_PSEPU (I6LNY0)
FT   ACT_SITE        75
FT                   /note="Proton acceptor"
FT   Condition: K
FT   ACT_SITE        301
FT                   /note="Proton acceptor"
FT   Condition: Y
FT   BINDING         174
FT                   /ligand="substrate"
FT   Condition: R
FT   BINDING         349
FT                   /ligand="substrate"
FT   Condition: M
FT   MOD_RES         75
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT   Condition: K
FT   DISULFID        71..97
FT   Tag: Disulfide; Condition: C-x*-C
XX
Size: 380-445;
Related: None;
Template: I6LNY0; A0KLG5; Q88GJ9; I0J1I6; Q9KSE5;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.5 2023/06/01
//