AC   MF_02226;
DC   Protein; auto
TR   HAMAP; MF_02226; -; 1; level=0
XX
Names: AlluloseP_3_epimer
XX
ID   ALSE
case <OC:Enterobacterales>
DE   RecName: Full=D-allulose-6-phosphate 3-epimerase;
DE            EC=5.1.3.-;
GN   Name=alsE;
else
DE   RecName: Full=Putative D-allulose-6-phosphate 3-epimerase;
DE            EC=5.1.3.-;
end case
XX
CC   -!- FUNCTION: Catalyzes the reversible epimerization of D-allulose 6-
CC       phosphate to D-fructose 6-phosphate. Can also catalyze with lower
CC       efficiency the reversible epimerization of D-ribulose 5-phosphate to D-
CC       xylulose 5-phosphate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-allulose 6-phosphate = keto-D-fructose 6-phosphate;
CC         Xref=Rhea:RHEA:28426, ChEBI:CHEBI:57579, ChEBI:CHEBI:61519;
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC   -!- PATHWAY: Carbohydrate degradation; D-allose degradation.
CC   -!- SIMILARITY: Belongs to the ribulose-phosphate 3-epimerase family. AlsE
CC       subfamily.
XX
DR   PROSITE; PS01085; RIBUL_P_3_EPIMER_1; 1; trigger=no
DR   PROSITE; PS01086; RIBUL_P_3_EPIMER_2; 1; trigger=no
DR   Pfam; PF00834; Ribul_P_3_epim; 1; trigger=no
XX
KW   Carbohydrate metabolism
KW   Isomerase
KW   Metal-binding
XX
GO   GO:0034700; F:allulose 6-phosphate 3-epimerase activity
GO   GO:0046872; F:metal ion binding
GO   GO:0019316; P:D-allose catabolic process
XX
FT   From: ALSE_ECOLI (P32719)
FT   BINDING         140..143
FT                   /ligand="substrate"
FT   Optional; Condition: G-[FY]-[AT]-G
FT   BINDING         173..175
FT                   /ligand="substrate"
FT   Optional; Condition: D-G-S
FT   BINDING         195..197
FT                   /ligand="substrate"
FT   Optional; Condition: G-[TS]-S
FT   ACT_SITE        32
FT                   /note="Proton acceptor"
FT   Condition: D
FT   ACT_SITE        173
FT                   /note="Proton donor"
FT   Condition: D
FT   BINDING         30
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: H
FT   BINDING         32
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: D
FT   BINDING         63
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: H
FT   BINDING         173
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: D
FT   BINDING         6
FT                   /ligand="substrate"
FT   Optional; Condition: S
FT   BINDING         63
FT                   /ligand="substrate"
FT   Optional; Condition: H
XX
Size: 210-260;
Related: None;
Template: P32719;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.5 2022/11/19
//