AC   MF_02227;
DC   Protein; auto
TR   HAMAP; MF_02227; -; 1; level=0
XX
Names: RPE
XX
ID   RPE
DE   RecName: Full=Ribulose-phosphate 3-epimerase;
DE            EC=5.1.3.1;
GN   Name=rpe;
XX
CC   -!- FUNCTION: Catalyzes the reversible epimerization of D-ribulose 5-
CC       phosphate to D-xylulose 5-phosphate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-ribulose 5-phosphate = D-xylulose 5-phosphate;
CC         Xref=Rhea:RHEA:13677, ChEBI:CHEBI:57737, ChEBI:CHEBI:58121;
CC         EC=5.1.3.1;
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC       Note=Binds 1 divalent metal cation per subunit.;
CC   -!- PATHWAY: Carbohydrate degradation.
CC   -!- SIMILARITY: Belongs to the ribulose-phosphate 3-epimerase family.
XX
DR   PROSITE; PS01085; RIBUL_P_3_EPIMER_1; 1; trigger=no
DR   PROSITE; PS01086; RIBUL_P_3_EPIMER_2; 1; trigger=no
DR   Pfam; PF00834; Ribul_P_3_epim; 1; trigger=no
DR   NCBIfam; TIGR01163; rpe; 1; trigger=no
DR   PIRSF; PIRSF001461; RPE; 1; trigger=no
XX
KW   Carbohydrate metabolism
KW   Isomerase
KW   Metal-binding
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GO   GO:0046872; F:metal ion binding
GO   GO:0004750; F:D-ribulose-phosphate 3-epimerase activity
GO   GO:0019323; P:pentose catabolic process
XX
FT   From: RPE_ECOLI (P0AG07)
FT   BINDING         144..147
FT                   /ligand="substrate"
FT   Optional; Condition: G-[FY]-x-G
FT   BINDING         177..179
FT                   /ligand="substrate"
FT   Optional; Condition: D-G-G
FT   BINDING         199..200
FT                   /ligand="substrate"
FT   Optional; Condition: [GA]-S
FT   ACT_SITE        36
FT                   /note="Proton acceptor"
FT   Condition: D
FT   ACT_SITE        177
FT                   /note="Proton donor"
FT   Condition: D
FT   BINDING         34
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: H
FT   BINDING         36
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: D
FT   BINDING         68
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: H
FT   BINDING         177
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT   Group: 1; Condition: D
FT   BINDING         9
FT                   /ligand="substrate"
FT   Optional; Condition: S
FT   BINDING         68
FT                   /ligand="substrate"
FT   Optional; Condition: H
XX
Size: 200-280;
Related: None;
Template: P0AG07;
Scope:
 Archaea
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: in CUPNH
Plasmid: in CUPNH
Comments: None
XX
# Revision 1.7 2023/06/01
//