AC   MF_02229;
DC   Protein; auto
TR   HAMAP; MF_02229; -; 1; level=0
XX
Names: Deoxyribose1P_isomerase
XX
ID   DRDI
DE   RecName: Full=5-deoxyribose 1-phosphate isomerase;
DE            EC=5.3.1.-;
GN   Name=drdI;
XX
CC   -!- FUNCTION: Catalyzes the isomerization of 5-deoxy-alpha-D-ribose 1-
CC       phosphate to 5-deoxy-D-ribulose 1-phosphate, as part of a 5-deoxyribose
CC       salvage pathway that recycles this toxic radical SAM enzyme by-product
CC       to mainstream metabolites.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-deoxy-alpha-D-ribose 1-phosphate = 5-deoxy-D-ribulose 1-
CC         phosphate; Xref=Rhea:RHEA:61296, ChEBI:CHEBI:58749,
CC         ChEBI:CHEBI:144504;
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:61297;
CC   -!- PATHWAY: Carbohydrate degradation.
CC   -!- SIMILARITY: Belongs to the EIF-2B alpha/beta/delta subunits family.
CC       DrdI subfamily.
XX
DR   Pfam; PF01008; IF-2B; 1; trigger=no
DR   NCBIfam; TIGR00524; eIF-2B_rel; 1; trigger=no
DR   NCBIfam; TIGR00512; salvage_mtnA; 1; trigger=no
XX
KW   Carbohydrate metabolism
KW   Isomerase
XX
GO   GO:0016861; F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses
GO   GO:0019323; P:pentose catabolic process
XX
FT   From: DRDI_BACT7 (P0DTQ1)
FT   BINDING         49..51
FT                   /ligand="substrate"
FT   Condition: R-G-A
FT   BINDING         250..251
FT                   /ligand="substrate"
FT   Condition: N-K
FT   ACT_SITE        240
FT                   /note="Proton donor"
FT   Condition: D
FT   BINDING         92
FT                   /ligand="substrate"
FT   Condition: R
FT   BINDING         199
FT                   /ligand="substrate"
FT   Condition: Q
FT   SITE            160
FT                   /note="Transition state stabilizer"
FT   Condition: C
XX
Size: 340-390;
Related: MF_01678;
Template: P0DTQ1;
Scope:
 Bacteria
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.5 2023/06/01
//