AC   MF_03027;
DC   Protein; auto
TR   HAMAP; MF_03027; -; 1; level=0
XX
Names: BOP1
XX
case <OC:Fungi>
ID   ERB1
else
ID   BOP1
end case
case <OC:Vertebrata>
DE   RecName: Full=Ribosome biogenesis protein @gn(BOP1);
DE   AltName: Full=Block of proliferation 1 protein;
else case <OC:Fungi>
DE   RecName: Full=Ribosome biogenesis protein @gn(ERB1);
DE   AltName: Full=Eukaryotic ribosome biogenesis protein 1;
else
DE   RecName: Full=Ribosome biogenesis protein BOP1 homolog;
end case
case <OC:Vertebrata>
GN   Name=BOP1;
else case <OC:Fungi>
GN   Name=ERB1;
end case
XX
case <OC:Vertebrata>
CC   -!- FUNCTION: Component of the PeBoW complex, which is required for
CC       maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S
CC       ribosome.
else case <OC:Fungi>
CC   -!- FUNCTION: Component of the NOP7 complex, which is required for
CC       maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S
CC       ribosome.
else
CC   -!- FUNCTION: Required for maturation of ribosomal RNAs and formation of
CC       the large ribosomal subunit.
end case
case <OC:Mammalia>
CC   -!- SUBUNIT: Component of the PeBoW complex, composed of BOP1, PES1 and
CC       WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and
CC       WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
else case <OC:Vertebrata>
CC   -!- SUBUNIT: Component of the PeBoW complex, composed of @gn(BOP1),
CC       @gn(PES1) and @gn(WDR12). Within the PeBoW complex @gn(BOP1) interacts
CC       directly with @gn(PES1) and @gn(WDR12). The PeBoW complex also
CC       associates with the 66S pre-ribosome.
else case <OC:Fungi>
CC   -!- SUBUNIT: Component of the NOP7 complex, composed of @gn(ERB1),
CC       @gn(NOP7) and @gn(YTM1). Within the NOP7 complex @gn(ERB1) appears to
CC       interact directly with @gn(NOP7) and @gn(YTM1). The NOP7 complex also
CC       associates with the 66S pre-ribosome.
end case
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus. Nucleus, nucleoplasm.
CC   -!- SIMILARITY: Belongs to the WD repeat BOP1/ERB1 family.
XX
DR   PROSITE; PS00678; WD_REPEATS_1; 1; trigger=no
DR   PROSITE; PS50082; WD_REPEATS_2; 2; trigger=no
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2; trigger=no
DR   Pfam; PF08145; BOP1NT; 1; trigger=no
DR   Pfam; PF00400; WD40; 4; trigger=no
DR   REP; Repeat_WD40; WD40; 6-7; trigger=yes
XX
KW   Nucleus
KW   Ribosome biogenesis
KW   rRNA processing
XX
GO   GO:0043021; F:ribonucleoprotein complex binding
GO   GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO   GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO   GO:0042273; P:ribosomal large subunit biogenesis
GO   GO:0005634; C:nucleus
GO   GO:0005730; C:nucleolus
GO   GO:0030687; C:preribosome, large subunit precursor
XX
FT   None
XX
Size: 605-1032;
Related: None;
Template: Q14137; P97452; Q04660;
Scope:
 Eukaryota
Fusion:
 Nter: None
 Cter: None
Duplicate: in XENLA
Plasmid: None
Comments: None
XX
# Revision 1.8 2019/11/20
//