AC   MF_03028;
DC   Protein; auto
TR   HAMAP; MF_03028; -; 1; level=0
XX
Names: Pescadillo
XX
ID   PESC
case <OC:Caenorhabditis>
DE   RecName: Full=Pescadillo homolog;
DE   AltName: Full=Lipid depleted protein 7;
else case <OC:Fungi>
DE   RecName: Full=Pescadillo homolog;
DE   AltName: Full=Nucleolar protein 7 homolog;
else
DE   RecName: Full=Pescadillo homolog;
end case
case <OC:Vertebrata>
GN   Name=PES1;
else case <OC:Caenorhabditis>
GN   Name=lpd-7;
else case <OC:Fungi>
GN   Name=NOP7;
end case
XX
case <OC:Vertebrata>
CC   -!- FUNCTION: Component of the PeBoW complex, which is required for
CC       maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S
CC       ribosome.
else case <OC:Fungi>
CC   -!- FUNCTION: Component of the NOP7 complex, which is required for
CC       maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S
CC       ribosome.
else
CC   -!- FUNCTION: Required for maturation of ribosomal RNAs and formation of
CC       the large ribosomal subunit.
end case
case <OC:Mammalia>
CC   -!- SUBUNIT: Component of the PeBoW complex, composed of BOP1, PES1 and
CC       WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and
CC       WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
CC       Interacts with IRS1 and UBTF. May interact with MAP1B.
else case <OC:Vertebrata>
CC   -!- SUBUNIT: Component of the PeBoW complex, composed of @gn(BOP1),
CC       @gn(PES1) and @gn(WDR12). Within the PeBoW complex @gn(BOP1) interacts
CC       directly with @gn(PES1) and @gn(WDR12). The PeBoW complex also
CC       associates with the 66S pre-ribosome.
else case <OC:Fungi>
CC   -!- SUBUNIT: Component of the NOP7 complex, composed of @gn(ERB1),
CC       @gn(NOP7) and @gn(YTM1). Within the NOP7 complex @gn(ERB1) appears to
CC       interact directly with @gn(NOP7) and @gn(YTM1). The NOP7 complex also
CC       associates with the 66S pre-ribosome.
end case
case <OC:Mammalia>
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus. Nucleus, nucleoplasm.
CC       Chromosome. Note=Appears to localize to the periphery of metaphase
CC       chromosomes during mitosis and to the prenucleolar bodies that form in
CC       mitotic cells prior to the actual nucleoli.
else
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus. Nucleus, nucleoplasm.
end case
case <OC:Mammalia>
CC   -!- PTM: Sumoylated.
end case
CC   -!- SIMILARITY: Belongs to the pescadillo family.
XX
DR   PROSITE; PS50172; BRCT; 1; trigger=yes
DR   Pfam; PF00533; BRCT; 1; trigger=no
DR   Pfam; PF06732; Pescadillo_N; 1; trigger=no
DR   PROSITE; PS50312; ASP_RICH; 0-unlimited; trigger=strict
DR   PROSITE; PS50313; GLU_RICH; 0-unlimited; trigger=strict
DR   PROSITE; PS50318; LYS_RICH; 0-unlimited; trigger=strict
DR   PROSITE; PS50323; ARG_RICH; 0-unlimited; trigger=strict
DR   General; Coiled_coil; -; 0-unlimited; trigger=strict
XX
KW   Nucleus
KW   Ribosome biogenesis
KW   rRNA processing
case <OC:Mammalia>
KW   Chromosome
KW   Ubl conjugation
end case
XX
GO   GO:0043021; F:ribonucleoprotein complex binding
GO   GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO   GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO   GO:0042273; P:ribosomal large subunit biogenesis
GO   GO:0005634; C:nucleus
GO   GO:0005730; C:nucleolus
GO   GO:0030687; C:preribosome, large subunit precursor
XX
FT   None
XX
Size: 451-725;
Related: None;
Template: O00541; Q9EQ61; P79741; Q95Y89; Q9VL96; P53261;
Scope:
 Eukaryota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.9 2019/11/20
//