AC   MF_03056;
DC   Protein; auto
TR   HAMAP; MF_03056; -; 1; level=0
XX
Names: TRM82
XX
case <OC:Fungi>
ID   TRM82
DE   RecName: Full=tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit <gene_name>;
DE   AltName: Full=Transfer RNA methyltransferase 82;
else case <OC:Insecta>
ID   WUHO
DE   RecName: Full=tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit <gene_name>;
else case <OC:Vertebrata> or <OC:Dictyostelium>
ID   WDR4
DE   RecName: Full=tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit <gene_name>;
DE   AltName: Full=WD repeat-containing protein 4;
else
ID   WDR4
DE   RecName: Full=tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit;
DE   AltName: Full=WD repeat-containing protein 4 homolog;
end case
case <OC:Vertebrata> or <OC:Dictyostelium>
GN   Name=WDR4;
else case <OC:Fungi>
GN   Name=TRM82;
else case <OC:Insecta>
GN   Name=wuho;
end case
XX
case <OC:Drosophilidae>
CC   -!- FUNCTION: Required for the formation of N(7)-methylguanine at position
CC       46 (m7G46) in tRNA. In the complex, it is required to stabilize and
CC       induce conformational changes of the catalytic subunit. Required during
CC       gametogenesis.
else case <OC:Saccharomyces>
CC   -!- FUNCTION: Required for the formation of N(7)-methylguanine at position
CC       46 (m7G46) in tRNA, a modification required to maintain stability of
CC       tRNAs; its absence resulting in tRNA decay. In the complex, it is
CC       required to stabilize and induce conformational changes of the
CC       catalytic subunit.
else
CC   -!- FUNCTION: Required for the formation of N(7)-methylguanine at position
CC       46 (m7G46) in tRNA. In the complex, it is required to stabilize and
CC       induce conformational changes of the catalytic subunit.
end case
CC   -!- PATHWAY: tRNA modification; N(7)-methylguanine-tRNA biosynthesis.
case <OC:Vertebrata> or <OC:Dictyostelium>
CC   -!- SUBUNIT: Forms a heterodimer with the catalytic subunit @gn(METTL1).
else case <OC:Fungi>
CC   -!- SUBUNIT: Forms a heterodimer with the catalytic subunit @gn(TRM8).
else
CC   -!- SUBUNIT: Forms a heterodimer with the catalytic subunit.
end case
case <OC:Drosophilidae>
CC   -!- SUBCELLULAR LOCATION: Nucleus. Note=Localized to the nuclei of nurse
CC       cells, follicle cells and oocytes at early stages, from germarium to
CC       stage 4 egg chambers. Also present in the nuclei of spermatocytes and
CC       in the apical cells of the testes.
else
CC   -!- SUBCELLULAR LOCATION: Nucleus.
end case
CC   -!- SIMILARITY: Belongs to the WD repeat TRM82 family.
XX
case not <OC:Saccharomyces>
DR   REP; Repeat_WD40; WD40; 2-7; trigger=yes
end case
DR   PROSITE; PS00678; WD_REPEATS_1; 1; trigger=no
DR   PROSITE; PS50082; WD_REPEATS_2; 1; trigger=no
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1; trigger=no
DR   Pfam; PF00400; WD40; 1; trigger=no
XX
KW   Nucleus
KW   Repeat
KW   tRNA processing
KW   WD repeat
case <OC:Drosophilidae>
KW   Developmental protein
KW   Differentiation
KW   Oogenesis
KW   Spermatogenesis
end case
XX
GO   GO:0005634; C:nucleus
GO   GO:0030488; P:tRNA methylation
case <OC:Drosophilidae>
GO   GO:0007283; P:spermatogenesis
GO   GO:0048477; P:oogenesis
end case
XX
FT   From: TRM82_YEAST (Q03774)
case <OC:Saccharomyces>
FT   REPEAT          1..47
FT                   /note="WD 1"
FT   REPEAT          48..99
FT                   /note="WD 2"
FT   REPEAT          100..147
FT                   /note="WD 3"
FT   REPEAT          148..192
FT                   /note="WD 4"
FT   REPEAT          193..237
FT                   /note="WD 5"
FT   REPEAT          238..279
FT                   /note="WD 6"
FT   REPEAT          308..354
FT                   /note="WD 7"
end case
XX
Size: 340-569;
Related: None;
Template: P57081; Q03774;
Scope:
 Eukaryota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.5 2019/11/20
//