AC   MF_03057;
DC   Protein; auto
TR   HAMAP; MF_03057; -; 1; level=0
XX
Names: SDHAF2
XX
ID   SDHF2
DE   RecName: Full=Succinate dehydrogenase assembly factor 2, mitochondrial;
DE            Short=SDH assembly factor 2;
DE            Short=SDHAF2;
case <OC:Vertebrata>
GN   Name=SDHAF2; Synonyms=PGL2, SDH5;
else case <OC:Saccharomyces>
GN   Name=SDH5;
end case
XX
case <OC:Vertebrata>
CC   -!- FUNCTION: Plays an essential role in the assembly of succinate
CC       dehydrogenase (SDH), an enzyme complex (also referred to as respiratory
CC       complex II) that is a component of both the tricarboxylic acid (TCA)
CC       cycle and the mitochondrial electron transport chain, and which couples
CC       the oxidation of succinate to fumarate with the reduction of ubiquinone
CC       (coenzyme Q) to ubiquinol. Required for flavinylation (covalent
CC       attachment of FAD) of the flavoprotein subunit @gn(SDHA) of the SDH
CC       catalytic dimer.
CC   -!- SUBUNIT: Interacts with @gn(SDHA) within the SDH catalytic dimer.
else
CC   -!- FUNCTION: Plays an essential role in the assembly of succinate
CC       dehydrogenase (SDH), an enzyme complex (also referred to as respiratory
CC       complex II) that is a component of both the tricarboxylic acid (TCA)
CC       cycle and the mitochondrial electron transport chain, and which couples
CC       the oxidation of succinate to fumarate with the reduction of ubiquinone
CC       (coenzyme Q) to ubiquinol. Required for flavinylation (covalent
CC       attachment of FAD) of the flavoprotein subunit of the SDH catalytic
CC       dimer.
CC   -!- SUBUNIT: Interacts with the flavoprotein subunit within the SDH
CC       catalytic dimer.
end case
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix.
case not <AnyFeature:TransitM>
CC   -!- MISCELLANEOUS: This protein may be expected to contain an N-terminal
CC       transit peptide but none has been predicted.
end case
CC   -!- SIMILARITY: Belongs to the SDHAF2 family.
XX
DR   Pfam; PF03937; DUF339; 1; trigger=no
DR   General; TransitM; -; 0-1; trigger=yes
XX
KW   Chaperone
KW   Mitochondrion
XX
GO   GO:0006121; P:mitochondrial electron transport, succinate to ubiquinone
GO   GO:0018293; P:protein-FAD linkage
GO   GO:0005759; C:mitochondrial matrix
XX
FT   None
XX
Size: 119-310;
Related: None;
Template: Q9NX18; Q08230;
Scope:
 Eukaryota
Fusion:
 Nter: None
 Cter: None
Duplicate: in DROAN, DROER, DROME, DROMO, DROPE, DROPS, DROSE, DROSI, DROWI,
 DROYA
Plasmid: None
Comments: None
XX
# Version: 7
# Last updated date: 2019-11-20
# Created date: 2013-08-23
//