AC   MF_03058;
DC   Protein; auto
TR   HAMAP; MF_03058; -; 1; level=0
XX
Names: VMA21
XX
ID   VMA21
case <OC:Vertebrata> or <OC:Fungi>
DE   RecName: Full=Vacuolar ATPase assembly integral membrane protein <gene_name>;
GN   Name=VMA21;
else
DE   RecName: Full=Vacuolar ATPase assembly integral membrane protein VMA21 homolog;
end case
XX
case <OC:Saccharomyces>
CC   -!- FUNCTION: Functions with VOA1 in assembly of the integral membrane
CC       sector (also called V0 sector) of the V-ATPase in the endoplasmic
CC       reticulum. Escorts the assembled V0 sector in COPII vesicles. Also
CC       required for normal packaging of the SNARE BOS1 and possibly the ER to
CC       Golgi transport receptor ERV29.
else
CC   -!- FUNCTION: Required for the assembly of the V0 complex of the vacuolar
CC       ATPase (V-ATPase) in the endoplasmic reticulum.
end case
case <OC:Mammalia>
CC   -!- SUBUNIT: Associates with the V0 complex of the vacuolar ATPase (V-
CC       ATPase).
end case
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass
CC       membrane protein. Endoplasmic reticulum-Golgi intermediate compartment
CC       membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-
CC       coated vesicle membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the VMA21 family.
XX
DR   General; Transmembrane; -; 2; trigger=strict
DR   ADD_TOPO_DOMAIN; Cytoplasmic; -; 2; trigger=yes
DR   ADD_TOPO_DOMAIN; Lumenal; -; 1; trigger=yes
XX
KW   Cytoplasmic vesicle
KW   Endoplasmic reticulum
KW   Membrane
KW   Transmembrane
KW   Transmembrane helix
XX
GO   GO:0070072; P:vacuolar proton-transporting V-type ATPase complex assembly
GO   GO:0005789; C:endoplasmic reticulum membrane
GO   GO:0012507; C:ER to Golgi transport vesicle membrane
XX
FT   From: VMA21_YEAST (P41806)
case <OC:Fungi>
FT   MOTIF           74..77
FT                   /note="Prevents secretion from ER"
FT   Condition: K-K-x-x
end case
XX
Size: 72-127;
Related: None;
Template: Q3ZAQ7; P41806;
Scope:
 Eukaryota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.6 2019/11/20
//