AC   MF_03059;
DC   Protein; auto
TR   HAMAP; MF_03059; -; 1; level=0
XX
Names: mEF_G_2
XX
ID   RRF2M
DE   RecName: Full=Ribosome-releasing factor 2, mitochondrial;
DE            Short=RRF2mt;
DE   AltName: Full=Elongation factor G 2, mitochondrial;
DE            Short=mEF-G 2;
DE            Short=EF-G2mt;
case <OC:Vertebrata>
GN   Name=GFM2; Synonyms=EFG2;
else case <OC:Fungi>
GN   Name=MEF2;
end case
XX
case <OC:Vertebrata>
CC   -!- FUNCTION: Mitochondrial GTPase that mediates the disassembly of
CC       ribosomes from messenger RNA at the termination of mitochondrial
CC       protein biosynthesis. Acts in collaboration with @gn(MRRF). GTP
CC       hydrolysis follows the ribosome disassembly and probably occurs on the
CC       ribosome large subunit. Not involved in the GTP-dependent ribosomal
CC       translocation step during translation elongation.
else
CC   -!- FUNCTION: Mitochondrial GTPase that mediates the disassembly of
CC       ribosomes from messenger RNA at the termination of mitochondrial
CC       protein biosynthesis. Not involved in the GTP-dependent ribosomal
CC       translocation step during translation elongation.
end case
CC   -!- SUBCELLULAR LOCATION: Mitochondrion.
case not <AnyFeature:TransitM>
CC   -!- MISCELLANEOUS: This protein may be expected to contain an N-terminal
CC       transit peptide but none has been predicted.
end case
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. EF-G/EF-2
CC       subfamily.
XX
DR   PROSITE; PS00301; G_TR_1; 1; trigger=no
DR   PROSITE; PS51722; G_TR_2; 1; trigger=no
DR   Pfam; PF00679; EFG_C; 1; trigger=no
DR   Pfam; PF03764; EFG_IV; 1; trigger=no
DR   Pfam; PF00009; GTP_EFTU; 1; trigger=no
DR   Pfam; PF03144; GTP_EFTU_D2; 1; trigger=no
DR   PRINTS; PR00315; ELONGATNFCT; 1; trigger=no
DR   NCBIfam; TIGR00231; small_GTP; 1; trigger=no
DR   General; TransitM; -; 0-1; trigger=yes
XX
KW   GTP-binding
KW   Mitochondrion
KW   Nucleotide-binding
KW   Protein biosynthesis
XX
GO   GO:0003924; F:GTPase activity
GO   GO:0005525; F:GTP binding
GO   GO:0032543; P:mitochondrial translation
GO   GO:0032790; P:ribosome disassembly
GO   GO:0005739; C:mitochondrion
XX
FT   From: RRF2M_HUMAN (Q969S9)
FT   BINDING         77..84
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT   Condition: A-H-I-D-[AG]-G-K-T
FT   BINDING         141..145
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT   Condition: D-T-P-G-H
FT   BINDING         195..198
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT   Condition: N-K-[ML]-D
XX
Size: 692-931;
Related: None;
Template: Q969S9; P39677;
Scope:
 Eukaryota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.11 2023/06/01
//