AC   MF_03069;
DC   Protein; auto
TR   HAMAP; MF_03069; -; 1; level=0
XX
Names: Kintoun
XX
ID   KTU
case <OC:Vertebrata>
DE   RecName: Full=Protein kintoun;
DE   AltName: Full=Dynein assembly factor 2, axonemal;
else case <OC:Drosophilidae>
DE   RecName: Full=Protein kintoun;
DE   AltName: Full=Dynein assembly factor 2, axonemal homolog;
DE   AltName: Full=PP1-interacting protein 20;
else
DE   RecName: Full=Protein kintoun;
DE   AltName: Full=Dynein assembly factor 2, axonemal homolog;
end case
case <OC:Vertebrata>
GN   Name=DNAAF2; Synonyms=KTU;
else case <OC:Drosophilidae>
GN   Name=Nop17l; Synonyms=Ppi20;
end case
XX
CC   -!- FUNCTION: Required for cytoplasmic pre-assembly of axonemal dyneins,
CC       thereby playing a central role in motility in cilia and flagella.
CC       Involved in pre-assembly of dynein arm complexes in the cytoplasm
CC       before intraflagellar transport loads them for the ciliary compartment.
case <OC:Mammalia>
CC   -!- SUBUNIT: Interacts with CFAP300. Interacts with DNAI2 and HSPA1A.
CC       Interacts with DYX1C1. Interacts with PIH1D3.
else case <OC:Drosophilidae>
CC   -!- SUBUNIT: Interacts with Pp1alpha-96A, Pp1-87B, Pp1-13C and flw.
end case
case <OC:Vertebrata>
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Note=Localizes in the apical cytoplasm
CC       around the gamma-tubulin-positive pericentriolar region, not in the
CC       cilia.
else
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
end case
CC   -!- SIMILARITY: Belongs to the PIH1 family. Kintoun subfamily.
XX
DR   Pfam; PF08190; PIH1; 1; trigger=no
XX
KW   Cytoplasm
XX
GO   GO:0005737; C:cytoplasm
GO   GO:0060285; P:cilium-dependent cell motility
GO   GO:0070286; P:axonemal dynein complex assembly
XX
FT   None
XX
Size: 566-906;
Related: None;
Template: Q9NVR5; Q8BPI1; B6F1W5;
Scope:
 Eukaryota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.5 2019/11/20
//