AC   MF_03131;
DC   Protein; auto
c?   <OC:Eukaryota>
TR   HAMAP; MF_00020; -; 1; level=0
XX
Names: Acetate_kinase_euk
XX
ID   ACKA
DE   RecName: Full=Probable acetate kinase;
DE            EC=2.7.2.1;
DE   AltName: Full=Acetokinase;
XX
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetate + ATP = acetyl phosphate + ADP; Xref=Rhea:RHEA:11352,
CC         ChEBI:CHEBI:22191, ChEBI:CHEBI:30089, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:456216; EC=2.7.2.1;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis;
CC       acetyl-CoA from acetate: step 1/2.
CC   -!- SIMILARITY: Belongs to the acetokinase family.
XX
DR   Pfam; PF00871; Acetate_kinase; 1; trigger=no
DR   PIRSF; PIRSF000722; Acetate_prop_kin; 1; trigger=no
DR   PRINTS; PR00471; ACETATEKNASE; 1; trigger=no
DR   NCBIfam; TIGR00016; ackA; 1; trigger=no
DR   PROSITE; PS01075; ACETATE_KINASE_1; 1; trigger=no
DR   PROSITE; PS01076; ACETATE_KINASE_2; 1; trigger=no
XX
KW   ATP-binding
KW   Kinase
KW   Magnesium
KW   Metal-binding
KW   Nucleotide-binding
KW   Transferase
XX
GO   GO:0008776; F:acetate kinase activity
GO   GO:0000287; F:magnesium ion binding
GO   GO:0016310; P:phosphorylation
XX
FT   From: ACKA_METTE (P38502)
FT   BINDING         208..212
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Optional; Condition: H-x-G-x-G
FT   BINDING         283..285
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Optional; Condition: D-x-R
FT   BINDING         331..335
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Optional; Condition: G-[IVLM]-G-E-[NH]
FT   ACT_SITE        148
FT                   /note="Proton donor/acceptor"
FT   Condition: D
FT   BINDING         7
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: N
FT   BINDING         384
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT   Condition: E
FT   BINDING         14
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT   Optional; Condition: K
FT   BINDING         91
FT                   /ligand="substrate"
FT   Optional; Condition: R
FT   SITE            180
FT                   /note="Transition state stabilizer"
FT   Condition: H
FT   SITE            241
FT                   /note="Transition state stabilizer"
FT   Condition: R
XX
Size: 392-488;
Related: MF_00542; MF_01881!; MF_01882!;
Template: P0A6A3;
Scope:
 Eukaryota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.11 2023/06/01
//