AC   MF_03187;
DC   Protein; auto
TR   HAMAP; MF_03187; -; 1; level=0
XX
Names: Methyltr_EFM5
XX
case <OC:Vertebrata>
ID   EFMT1
DE   RecName: Full=EEF1A lysine methyltransferase 1;
DE            EC=2.1.1.-;
DE   AltName: Full=N(6)-adenine-specific DNA methyltransferase 2;
DE   AltName: Full=Protein-lysine N-methyltransferase N6AMT2;
GN   Name=EEF1AKMT1; Synonyms=N6AMT2;
else case <OC:Fungi>
ID   EFM5
DE   RecName: Full=Protein-lysine N-methyltransferase <gene_name>;
DE            EC=2.1.1.-;
DE   AltName: Full=Elongation factor methyltransferase 5;
GN   Name=EFM5;
else
DE   RecName: Full=Protein-lysine N-methyltransferase <locus_tag>;
DE            EC=2.1.1.-;
end case
XX
case <OC:Vertebrata>
CC   -!- FUNCTION: Protein-lysine methyltransferase that selectively catalyzes
CC       the trimethylation of EEF1A at 'Lys-79'.
else case <OC:Fungi>
CC   -!- FUNCTION: S-adenosyl-L-methionine-dependent protein-lysine N-
CC       methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-
CC       79'.
else
CC   -!- FUNCTION: S-adenosyl-L-methionine-dependent protein-lysine N-
CC       methyltransferase that methylates elongation factor 1-alpha.
end case
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. EFM5 family.
case <OC:Vertebrata>
CC   -!- CAUTION: Was originally thought to be an N(6)-adenine-specific DNA
CC       methyltransferase based on primary sequence and predicted secondary
CC       structure.
end case
XX
DR   Pfam; PF10237; N6-adenineMlase; 1; trigger=no
XX
KW   Cytoplasm
KW   Methyltransferase
KW   Transferase
XX
GO   GO:0005737; C:cytoplasm
GO   GO:0016279; F:protein-lysine N-methyltransferase activity
GO   GO:0018022; P:peptidyl-lysine methylation
XX
FT   None
XX
Size: 205-277;
Related: None;
Template: P53200;
Scope:
 Eukaryota
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.4 2019/11/20
//