AC   MF_03223;
DC   Protein; auto
TR   HAMAP; MF_03223; -; 1; level=0
XX
Names: Methyltr_EFM7
XX
ID   EFM7
DE   RecName: Full=Protein N-terminal and lysine N-methyltransferase EFM7;
DE            EC=2.1.1.-;
DE   AltName: Full=Elongation factor methyltransferase 7;
GN   Name=EFM7;
XX
CC   -!- FUNCTION: S-adenosyl-L-methionine-dependent protein methyltransferase
CC       that trimethylates the N-terminal glycine 'Gly-2' of elongation factor
CC       1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. EFM7 family.
XX
DR   PROSITE; PS51560; SAM_MT_NNT1; 1; trigger=no
DR   Pfam; PF10294; Methyltransf_16; 1; trigger=no
XX
KW   Cytoplasm
KW   Methyltransferase
KW   S-adenosyl-L-methionine
KW   Transferase
XX
GO   GO:0005737; C:cytoplasm
GO   GO:0071885; F:N-terminal protein N-methyltransferase activity
GO   GO:0016279; F:protein-lysine N-methyltransferase activity
GO   GO:0018013; P:N-terminal peptidyl-glycine methylation
GO   GO:0018027; P:peptidyl-lysine dimethylation
XX
FT   From: EFM7_YEAST (Q05874)
FT   BINDING         90..92
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: G-A-[GA]
FT   BINDING         64
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: W
FT   BINDING         112
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: D
FT   BINDING         144
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: W
FT   BINDING         171
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT   Condition: [SA]
XX
Size: 254-299;
Related: None;
Template: Q05874;
Scope:
 Eukaryota; Fungi
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.6 2022/11/19
//