AC   MF_04035;
DC   Protein; auto
TR   HAMAP; MF_04035; -; 1; level=0
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Names: HSV_GM
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ID   GM
DE   RecName: Full=Envelope glycoprotein M;
DE            Short=gM;
GN   Name=gM;
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CC   -!- FUNCTION: Envelope glycoprotein important for virion assembly and
CC       egress. Plays a role in the correct incorporation of gH-gL into virion
CC       membrane. Directs the glycoprotein N (gN) to the host trans-Golgi
CC       network.
CC   -!- SUBUNIT: Interacts (via N-terminus) with gN (via N-terminus). The gM-gN
CC       heterodimer forms the gCII complex.
CC   -!- SUBCELLULAR LOCATION: Virion membrane; Multi-pass membrane protein.
CC       Host Golgi apparatus, host trans-Golgi network. Host endosome membrane;
CC       Multi-pass membrane protein. Host nucleus inner membrane; Multi-pass
CC       membrane protein. Note=During virion morphogenesis, this protein
CC       accumulates in the trans-Golgi network where secondary envelopment
CC       occurs.
CC   -!- SIMILARITY: Belongs to the herpesviridae glycoprotein M family.
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DR   Pfam; PF01528; Herpes_glycop; 1; trigger=no
DR   PRINTS; PR00333; HSVINTEGRLMP; 1; trigger=no
DR   General; Transmembrane; -; 8; trigger=yes
DR   ADD_TOPO_DOMAIN; Intravirion; -; 5; trigger=yes
DR   ADD_TOPO_DOMAIN; Virion_surface; -; 4; trigger=yes
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KW   Disulfide bond
KW   Glycoprotein
KW   Host endosome
KW   Host Golgi apparatus
KW   Host membrane
KW   Host nucleus
KW   Membrane
KW   Transmembrane
KW   Transmembrane helix
KW   Viral envelope protein
KW   Virion
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GO   GO:0044175; C:host cell endosome membrane
GO   GO:0044178; C:host cell Golgi membrane
GO   GO:0044201; C:host cell nuclear inner membrane
GO   GO:0016020; C:membrane
GO   GO:0019031; C:viral envelope
GO   GO:0055036; C:virion membrane
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FT   From: GM_HHV11 (P04288)
FT   DISULFID        59
FT                   /note="Interchain (with gN)"
FT   Condition: C
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Size: 344-473;
Related: None;
Template: P04288; P16733;
Scope:
 Viruses; Herpesviridae
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
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# Revision 1.4 2022/09/29
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