AC   MF_04037;
DC   Protein; auto
TR   HAMAP; MF_04037; -; 1; level=0
XX
Names: HSV_GN
XX
ID   GN
DE   RecName: Full=Envelope glycoprotein N;
GN   Name=gN;
XX
CC   -!- FUNCTION: Envelope glycoprotein necessary for proper maturation of gM
CC       and modulation of its membrane fusion activity. Plays also a critical
CC       role in virion morphogenesis.
CC   -!- SUBUNIT: Interacts (via N-terminus) with gM (via N-terminus). The gM-gN
CC       heterodimer forms the gCII complex.
CC   -!- SUBCELLULAR LOCATION: Virion membrane; Single-pass type I membrane
CC       protein. Host membrane; Single-pass type I membrane protein. Host Golgi
CC       apparatus, host trans-Golgi network. Note=When coexpressed with gM,
CC       localizes in the host trans-Golgi network.
CC   -!- SIMILARITY: Belongs to the herpesviridae glycoprotein N family.
XX
DR   Pfam; PF03554; Herpes_UL73; 1; trigger=no
DR   Pfam; PF12522; UL73_N; 1; trigger=no
DR   Pfam; PF05702; Herpes_UL49_5; 1; trigger=no
DR   PIRSF; PIRSF038075; Herpes_UL49A_env; 1; trigger=no
case <Feature:Transmembrane==1>
DR   ADD_TOPO_DOMAIN; Virion_surface; -; 1; trigger=yes
DR   ADD_TOPO_DOMAIN; Intravirion; -; 1; trigger=yes
DR   General; Transmembrane; -; 1; trigger=yes
end case
DR   General; Signal; -; 0-1; trigger=yes
XX
KW   Disulfide bond
KW   Host Golgi apparatus
KW   Host membrane
KW   Membrane
KW   Transmembrane
KW   Transmembrane helix
KW   Viral envelope protein
KW   Virion
XX
GO   GO:0016020; C:membrane
GO   GO:0019031; C:viral envelope
GO   GO:0055036; C:virion membrane
XX
FT   From: GN_HHV11 (O09800)
case not <Feature:Transmembrane==1>
FT   TOPO_DOM        Nter..55
FT                   /note="Virion surface"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT   TOPO_DOM        77..Cter
FT                   /note="Intravirion"
end case
FT   DISULFID        46
FT                   /note="Interchain (with gM)"
FT   Condition: C
XX
Size: 84-171;
Related: None;
Template: O09800; P16795; P0C764;
Scope:
 Viruses; Herpesviridae
Fusion:
 Nter: None
 Cter: None
Duplicate: None
Plasmid: None
Comments: None
XX
# Revision 1.7 2022/09/29
//